2007, Number 4
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Rev Mex Anest 2007; 30 (4)
Caudal clonidine for open hip reduction in pediatric patients
González-Flores ML, Peralta-Zamora E, Zaragoza-Lemus G, Flores-Hernández SS
Language: Spanish
References: 20
Page: 201-207
PDF size: 116.38 Kb.
ABSTRACT
Objective: To compare the efficacy and safety of caudal block with clonidine/bupivacaine versus caudal block with bupivacaine alone.
Methods: The study was conducted with forty-six children, aged 1 to 8 years scheduled for open reduction of the hip in ASA physical status I-II. Inhalatory sedation was with sevoflurane (4.0 vol%); Group I caudal block was with bupivacaine 0.25% 1.4 mL/kg and group 2 caudal block was with clonidine 2 µg/kg plus bupivacaine 0.25% 1.4mL/kg. Anesthesia was maintained with sevoflurane 10-1.5 vol%.
Results: The duration of surgery and anesthesia were the same. Group 2 had longer duration of analgesia than group 1 (13.06 vs 7.65 h). The blood pressure and cardiac rate were lower in group 2 (p‹.05). Arterial saturation was similar. Group 2 had longer sedation. 17.3% of group 1 and 8.7% of group 2 had vomit (p = 0.03).
Conclusions: Adding clonidine (2 µg/kg) to bupivacaine (0.25% 1.4 ml/kg) provided good post-surgical analgesia without significant haemodynamic changes.
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