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Centro Universitario de Ciencias de la Salud de la Universidad de Guadalajara y del OPD Hospitales Civiles de Guadalajara

2006, Number 1

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Inv Salud 2006; 8 (1)

Diabetes, oxidative stress and antioxidants

Ramos IML, Batista GCM, Gómez MBC, Zamora PAL

Language: Spanish
References: 64
Page: 7-15
PDF size: 475.98 Kb.


ABSTRACT

Diabetes mellitus is a group of metabolic diseases characterized by high blood glucose levels. Over time, diabetes can lead to blindness, kidney failure, nerve damage and atherosclerosis, what make it one of the main causes of morbidity and mortality. Nowadays some evidences show that such complications, due mainly to a biochemical imbalance are produced by the excessive production of free radicals (FR), which causes oxidative damage to the bio-molecules and that cannot be counteract by the antioxidant systems. Fortunately, this damage can be avoided or diminished with the administration of adequate doses of exogenous antioxidants (high-quality supplements), which could permit to the diabetic patients to have a better quality of life, because it is to expect that the micro and macro vascular complications caused mainly by the excessive production of FR diminish with the administration of antioxidant compounds.


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