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Centro Universitario de Ciencias de la Salud de la Universidad de Guadalajara y del OPD Hospitales Civiles de Guadalajara

2006, Número 1

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Inv Salud 2006; 8 (1)


Diabetes, estrés oxidativo y antioxidantes

Ramos IML, Batista GCM, Gómez MBC, Zamora PAL

Idioma: Español
Referencias bibliográficas: 64
Paginas: 7-15
Archivo PDF: 475.98 Kb.


RESUMEN

La diabetes mellitus es un síndrome caracterizado por la concentración elevada de glucosa sanguínea. La enfermedad es progresiva y está asociada con alto riesgo de ateroesclerosis, daño renal, neuronal y ceguera; lo que la convierte en una de las principales causas de morbi-mortalidad. Actualmente, existen evidencias de que tales complicaciones se deben principalmente a que se produce un desequilibrio bioquímico propiciado por la producción excesiva de radicales libres (RL), lo que provoca daño oxidativo a las biomoléculas y que no puede ser contrarrestado por los sistemas antioxidantes de defensa. Afortunadamente, dicho daño se puede evitar o disminuir con la administración de dosis adecuadas de antioxidantes exógenos (suplementos de alta calidad), lo que pudiera permitir a los pacientes diabéticos tener mejor calidad de vida, pues es de esperar que las complicaciones micro y macrovasculares ocasionadas principalmente por la producción excesiva de RL disminuyan con la administración de los antioxidantes.


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