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Centro de Investigaciones Regionales Dr. Hideyo Noguchi, Universidad Autónoma de Yucatán

2006, Number 1

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Rev Biomed 2006; 17 (1)

1918 Influenza: The mother of all pandemics

Taubenberger JK, Morens DM

Language: English
References: 39
Page: 69-79
PDF size: 130.13 Kb.


ABSTRACT

The "Spanish" influenza pandemic of 1918–1919, which caused »50 million deaths worldwide, remains an ominous warning to public health. Many questions about its origins, its unusual epidemiologic features, and the basis of its pathogenicity remain unanswered. The public health implications of the pandemic therefore remain in doubt even as we now grapple with the feared emergence of a pandemic caused by H5N1 or other virus. However, new information about the 1918 virus is emerging, for example, sequencing of the entire genome from archival autopsy tissues. But, the viral genome alone is unlikely to provide answers to some critical questions. Understanding the 1918 pandemic and its implications for future pandemics requires careful experimentation and in-depth historical analysis.


REFERENCES

  1. 1.- Frost WH. Statistics of influenza morbidity. Public Health Rep. 1920;35:584–97.

  2. 2.- Burnet F, Clark E. Influenza: a survey of the last 50 years in the light of modern work on the virus of epidemic influenza. Melbourne: MacMillan; 1942.

  3. 3.- Marks G, Beatty WK. Epidemics. New York: Scribners; 1976.

  4. 4.- Rosenau MJ, Last JM. Maxcy-Rosenau preventative medicine and public health. New York: Appleton-Century-Crofts; 1980.

  5. 5.- Crosby A. America's forgotten pandemic. Cambridge (UK): Cambridge University Press;1989.

  6. 6.- Patterson KD, Pyle GF. The geography and mortality of the 1918 influenza pandemic. Bull Hist Med. 1991; 65:4–21.

  7. 7.- Johnson NPAS, Mueller J. Updating the accounts: global mortality of the 1918–1920 "Spanish" influenza pandemic. Bull Hist Med. 2002; 76:105–15.

  8. 8.- Shope RE. The incidence of neutralizing antibodies for swine influenza virus in the sera of human beings of different ages. J Exp Med. 1936; 63:669–84.

  9. 9.- Kendal AP, Noble GR, Skehel JJ, Dowdle WR. Antigenic similarity of influenza A (H1N1) viruses from epidemics in 1977–1978 to "Scandinavian" strains isolated in epidemics of 1950–1951. Virology. 1978; 89:632–6.

  10. 10.- Taubenberger JK, Reid AH, Krafft AE, Bijwaard KE, Fanning TG. Initial genetic characterization of the 1918 "Spanish" influenza virus. Science. 1997; 275:1793–6.

  11. 11.- Basler CF, Reid AH, Dybing JK, Janczewski TA, Fanning TG, Zheng H, et al. Sequence of the 1918 pandemic influenza virus nonstructural gene (NS) segment and characterization of recombinant viruses bearing the 1918 NS genes. Proc Natl Acad Sci U S A. 2001; 98:2746–51.

  12. 12.- Reid AH, Fanning TG, Hultin JV, Taubenberger JK. Origin and evolution of the 1918 "Spanish" influenza virus hemagglutinin gene. Proc Natl Acad Sci U S A. 1999;96:1651–6.

  13. 13.- Reid AH, Fanning TG, Janczewski TA, Lourens RM, Taubenberger JK. Novel origin of the 1918 pandemic influenza virus nucleoprotein gene segment. J Virol. 2004; 78:12462–70.

  14. 14.- Reid AH, Fanning TG, Janczewski TA, McCall S, Taubenberger JK. Characterization of the 1918 "Spanish" influenza virus matrix gene segment. J Virol. 2002; 76:10717–23.

  15. 15.- Reid AH, Fanning TG, Janczewski TA, Taubenberger JK. Characterization of the 1918 "Spanish" influenza virus neuraminidase gene. Proc Natl Acad Sci U S A. 2000; 97:6785–90.

  16. 16.- Reid AH, Janczewski TA, Lourens RM, Elliot AJ, Daniels RS, Berry CL, et al. 1918 influenza pandemic caused by highly conserved viruses with two receptor-binding variants. Emerg Infect Dis. 2003; 9:1249–53.

  17. 17.- Taubenberger JK, Reid AH, Lourens RM, Wang R, Jin G, Fanning TG. Characterization of the 1918 influenza virus polymerase genes. Nature. 2005; 437:889–93.

  18. 18.- Reid AH, Taubenberger JK. The 1918 flu and other influenza pandemics: "over there" and back again. Lab Invest. 1999; 79:95–101.

  19. 19.- Reid AH, Taubenberger JK, Fanning TG. Evidence of an absence: the genetic origins of the 1918 pandemic influenza virus. Nat Rev Microbiol. 2004; 2:909–14.

  20. 20.- Taubenberger JK, Reid AH, Fanning TG. The 1918 influenza virus: a killer comes into view. Virology. 2000; 274:241–5.

  21. 21.- Jordan E. Epidemic influenza: a survey. Chicago: American Medical Association, 1927.

  22. 22.- Capps J, Moody A. The recent epidemic of grip. JAMA. 1916; 67:1349–50.

  23. 23.- Oxford JS, Sefton A, Jackson R, Innes W, Daniels RS, Johnson NP. World War I may have allowed the emergence of "Spanish" influenza. Lancet Infect Dis. 2002; 2:111–4.

  24. 24.- Fanning TG, Slemons RD, Reid AH, Janczewski TA, Dean J, Taubenberger JK. 1917 avian influenza virus sequences suggest that the 1918 pandemic virus did not acquire its hemagglutinin directly from birds. J Virol. 2002; 76:7860–2.

  25. 25.- Reid AH, Fanning TG, Slemons RD, Janczewski TA, Dean J, Taubenberger JK. Relationship of pre-1918 avian influenza HA and NP sequences to subsequent avian influenza strains. Avian Dis. 2003; 47:921–5.

  26. 26.- Bean W, Schell M, Katz J, Kawaoka Y, Naeve C, Gorman O, et al. Evolution of the H3 influenza virus hemagglutinin from human and nonhuman hosts. J Virol. 1992; 66:1129–38.

  27. 27.- Weis W, Brown JH, Cusack S, Paulson JC, Skehel JJ, Wiley DC. Structure of the influenza virus haemagglutinin complexed with its receptor, sialic acid. Nature. 1988; 333:426–31.

  28. 28.- Gambaryan AS, Tuzikov AB, Piskarev VE, Yamnikova SS, Lvov DK, Robertson JS, et al. Specification of receptor-binding phenotypes of influenza virus isolates from different hosts using synthetic sialylglycopolymers: non-egg-adapted human H1 and H3 influenza A and influenza B viruses share a common high binding affinity for 6'-sialyl(N-acetyllactosamine). Virology. 1997; 232:345–50.

  29. 29.- Matrosovich M, Gambaryan A, Teneberg S, Piskarev VE, Yamnikova SS, Lvov DK, et al. Avian influenza A viruses differ from human viruses by recognition of sialyloigosaccharides and gangliosides and by a higher conservation of the HA receptor-binding site. Virology. 1997; 233:224–34.

  30. 30.- Glaser L, Stevens J, Zamarin D, Wilson IA, Garcia-Sastre A, Tumpey TM, et al. A single amino acid substitution in the 1918 influenza virus hemagglutinin changes the receptor binding specificity. J Virol. 2005; 79:11533–6.

  31. 31.- Kobasa D, Takada A, Shinya K, Hatta M, Halfmann P, Theriault S, et al. Enhanced virulence of influenza A viruses with the haemagglutinin of the 1918 pandemic virus. Nature. 2004; 431:703–7.

  32. 32.- Kash JC, Basler CF, Garcia-Sastre A, Carter V, Billharz R, Swayne DE, et al. Global host immune response: pathogenesis and transcriptional profiling of type A influenza viruses expressing the hemagglutinin and neuraminidase genes from the 1918 pandemic virus. J Virol. 2004; 78:9499–511.

  33. 33.- Grove RD, Hetzel AM. Vital statistics rates in the United States: 1940–1960. Washington: US Government Printing Office, 1968.

  34. 34.- Linder FE, Grove RD. Vital statistics rates in the United States: 1900–1940. Washington: US Government Printing Office, 1943.

  35. 35.- Simonsen L, Clarke MJ, Schonberger LB, Arden NH, Cox NJ, Fukuda K. Pandemic versus epidemic influenza mortality: a pattern of changing age distribution. J Infect Dis 1998; 178:53–60.

  36. 36.- Frost WH. The epidemiology of influenza. Public Health Rep. 1919; 34:1823–61.

  37. 37.- Collins SD. Age and sex incidence of influenza and pneumonia morbidity and mortality in the epidemic of 1928-1929 with comparative data for the epidemic of 1918–1919. Public Health Rep. 1931; 46:1909–37.

  38. 38.- Majde JA. Influenza: Learn from the past. ASM News. 1996; 62:514.

  39. 39.- Peiris JS, Yu WC, Leung CW, Cheung CY, Ng WF, Nicholls JM, et al. Re-emergence of fatal human influenza A subtype H5N1 disease. Lancet. 2004; 363:617–9.




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