2006, Número 1
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Rev Biomed 2006; 17 (1)
Influenza en 1918: La madre de todas las pandemias
Taubenberger JK, Morens DM
Idioma: Ingles.
Referencias bibliográficas: 39
Paginas: 69-79
Archivo PDF: 130.13 Kb.
RESUMEN
La pandemia de influenza “Española” de 1918-1919, causó alrededor de 50 millones de muertes alrededor del mundo y permanece como una ominosa advertencia para la salud pública. Muchas preguntas sobre su origen, sus características epidemiológicas poco comunes y las bases de su patogenia permanecen sin respuesta. Por lo tanto, las implicaciones en salud pública de esta pandemia, aún nos hacen dudar de cómo vamos a enfrentarnos con la temida emergencia de una pandemia causada por el H5N1 o por otros virus. Sin embargo, nueva información acerca del virus de 1918 está emergiendo, como la secuenciación completa del genoma del virus en tejidos de autopsia archivados. Pero el genoma viral solo, es poco factible que proporcione respuestas a algunas preguntas críticas. Entender la pandemia de 1918 y sus implicaciones para futuras pandemias requiere de una cuidadosa experimentación y un profundo análisis histórico.
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