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2007, Number 1

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Vet Mex 2007; 38 (1)

What are stem cells or “mother cells”?

Anzaldúa ASR, Juárez MML, Villaseñor GH, Ríos MMC, Cornejo CMA, Meraz RMA

Language: English/Spanish
References: 96
Page: 81-104
PDF size: 1740.06 Kb.


ABSTRACT

This paper presents an updated review of the main general aspects of stem cells: historical background; defi nition of stem cells based on their main characteristics (degree of differentiation, pluripotent potential, self-renewing capacity and reintregration to embryonic tissue); classifi cation of stem cells by their degree of differentiation (totipotent stem cells, pluripotent stem cells, multipotent stem cells, and tissue-specifi c stem cells); origins of pluripotent stem cells (embryonic carcinoma cells, embryonic stem cells, and embryonic germ cells); main methods to obtain embryonic stem cells (use of morulae, complete blastocysts and immunosurgery of inner cell mass); main methods to obtain adult stem cells (purifi cation in peripheral blood, umbilical cord blood, whole bone marrow, and nervous tissue).


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