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2007, Número 1

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Vet Mex 2007; 38 (1)


¿Qué son las células troncales o “células madre”?

Anzaldúa ASR, Juárez MML, Villaseñor GH, Ríos MMC, Cornejo CMA, Meraz RMA

Idioma: Español/Inglés
Referencias bibliográficas: 96
Paginas: 81-104
Archivo PDF: 1740.06 Kb.


RESUMEN

En el presente trabajo se realiza una revisión actualizada sobre los principales aspectos generales de las células troncales: antecedentes históricos, defi nición de las células troncales con base en sus principales características (grado de indiferenciación, pluripotencialidad, capacidad de autorrenovación y reintegración a tejidos embrionarios); clasificación de las células troncales por su grado de diferenciación (células troncales totipotenciales, células troncales pluripotenciales, células troncales multipotenciales y células troncales de tejidos y órganos específi cos); origen de las células troncales pluripotenciales (células de carcinoma embrionario, células troncales embrionarias y células germinales embrionarias); principales métodos para obtener células troncales embrionarias (utilización de mórulas, blastocistos completos e inmunocirugía del macizo celular interno); principales métodos para obtener células troncales de tejidos adultos (purifi cación de sangre periférica, de sangre de cordón umbilical, de médula ósea completa y de tejido nervioso).


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