Treviño-Báez JD, Hernández-Herrera RJ

Language: Spanish
References: 22
Page: 243-248
PDF size: 122.31 Kb.

ABSTRACT

Introduction: during the neonatal period seventy to ninety percent of very low birth weight (VLBW) infants (birth weight ‹ 1500 g), are transfused with red blood cells (RBC) at least once; that represents infectious, biochemical, immunologic and oxidative risks. The objective of this paper is to describe the epidemiological profile of the VLBW infants that are transfused with RBC.
Methodology: a retrospective review of 61 VLBW newborns admitted to the Neonatology Unit of a tertiary care hospital in Monterrey, México was conducted. The sample was collected consecutively. The information included the newborns epidemiological profile and the characteristics of transfusion events.
Results: the prevalence of transfused newborns was 70.5 %, 82 transfusions were in the early postnatal period (‹ 28 days) and 32 in the late postnatal period (≥ 28 days); 43.9 % of newborns had mechanical ventilation and their fraction of inspired oxygen was ≥ 0.3. Mean birth weight and standard deviation of VLBW newborns were 1206 ± 198 g; the hematocrit before transfusion was 33.63 ± 4.17 mg/dL, and the RBC volume per transfusion was 16.85 ± 4.85 mL. On average, the newborns had two donors and two transfusions.
Conclusions: the epidemiological profile of the newborns included in this analysis was similar to published international reports. The transfusion characteristics suggest the possibility to apply restrictive guidelines and to evaluate a single-donor blood program for these newborns.

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