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Revista Latinoamericana de Microbiología

2004, Number 1-2

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Microbiología 2004; 46 (1-2)

The PQQ-dehydrogenases.A novel example of bacterial quinoproteins

Flores-Encarnación M, Sánchez-Cuevas M, Ortiz-Gutiérrez F

Language: Spanish
References: 95
Page: 47-59
PDF size: 146.94 Kb.


ABSTRACT

The word “quinoprotein” describes four groups of different enzymes which have cofactors containing o-quinones. Pyrrolo-quinoline quinone (PQQ) is not covalently attached. PQQ is the cofactor of several quinoprotein bacterial dehydrogenases including glucose dehydrogenase (G-DH), alcohol dehydrogenase (A-DH) and aldehyde dehydrogenase (AL-DH). These dehydrogenases are located in the periplasm of Gram-negative bacteria. This report summarises the structural properties of quinoprotein dehydrogenases, such as the biological functions and biotechnological aspects more important.


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