2007, Number 1
<< Back Next >>
Cir Cir 2007; 75 (1)
Inappropriate use of antibiotics in acute appendicitis. A survey of Mexican surgeons
Corona-Cruz JF, Melchor-Ruan J, Gracida-Mancilla NI, Vega-Chavaje GR, Sánchez-Lozada R
Language: Spanish
References: 24
Page: 25-30
PDF size: 65.00 Kb.
ABSTRACT
Background: Appendectomy is the most common non-elective surgery. The postoperative use of antibiotics depends on the stage of the appendix at the time of surgery. Several classifications establish that state. We determine if these classifica-tions are known and used by Mexican surgeons.
Methods: A descriptive and observational study was performed. A questionnaire was completed by surgeons asking the following questions: Do you use a classification for acute appendicitis?
2) Which classification do you prefer? 3) Do you use antibiotics postoperatively? 4) For what period of time do you administer antibiotics postoperatively? We evaluated if the postoperative treatment is influenced by the use of a classification, using the χ
2 test.
Results: One hundred and forty two surgeons were interviewed, 99 % used a classification, and 48 % indicated postoperative antibiotics, despite the stage of the disease, monotherapy (69 %), and for three doses (60 %). Fifty two percent used antibiotic only in advanced stages, with two different types (61 %), and from 7 to 10 days (66 %). We did not find any statistical difference in management, regardless of whether or not an appendicitis classification was used.
Conclusions: Although most surgeons use one classification for acute appendicitis, this does not influence postoperative treatment. This incongruity results in the unjustified use of antibiotics.
REFERENCES
Margenthaler JA, Longo WE, Virgo KS, et al. Risk factors for adverse outcome after the surgical treatment of appendicitis in adults. Ann Surg 2003;238:59-66.
Athié-Gutiérrez C, Guizar-Bermúdez C, Rivera-Reyes HH. Epidemio-logía de la patología abdominal aguda en el servicio de urgencias del Hospital General de México. Análisis de 30 años. Cir Gen 1999:21; 99-104.
Hardin DM. Acute appendicitis: review and update. Am Fam Physician 1999;60:2027-2036.
Rucinski J, Fabian T, Panagopoulos G, et al. Gangrenous and perforated appendicitis: a meta-analytic study of 2532 patients indicates that the incision should be closed primarily. Surgery 2000;127:136-141.
Andersen BR, Kallehave FL, Andersen HK. Antibiotic versus placebo for prevention of postoperative infection after appendectomy. The Cochrane Database of Systematic Reviews;2003.
Temple CL, Huchcroft SA, Temple WJ. The natural history of appendicitis in adults. Ann Surg 1995;221:278-281.
Lewis FR, Holcroft JW, Boey J, Dunphy JE. Appendicitis: a critical review of diagnosis and treatment in 1,000 cases. Arch Surg 1975; 110:677-684.
Chen C, Botelho C, Cooper A, et al. Current practice patterns in the treatment of perforated appendicitis in children. J Am Coll Surg 2003;196:212-221.
Newman K, Ponsky T, Kittle K, et al. Appendicitis 2000: variability in practice, outcomes, and resources utilization at thirty pediatric hospitals. J Pediatr Surg 2003;38:372-379.
Keller MS, McBride WJ, Vane DW. Management of complicated appendicitis. A rationale approach based on clinical course. Arch Surg 1996;131:261-264.
Guzmán-Valdivia GG. Una clasificación útil en apendicitis aguda. Rev Gastroenterol Mex 2003;68:261-265.
Helmer KS, Robinson EK, Lally KP, et al. Standardized patient care guidelines reduce infectious morbidity in appendectomy patients. Am J Surg 2002;183:608-613.
Bennion RS, Baron EJ, Thompson JE, et al. The bacteriology of gangrenous and perforated appendicitis—revisited. Ann Surg 1990; 211:165-171.
Baron EJ, Bennion RS, Thompson JE, et al. A microbial comparison between acute and complicated appendicitis. Clin Infect Dis 1992;14:227-231.
Winslow RE, Dean RE, Harley JW. Acute nonperforating appendicitis. Arch Surg 1983;118:651-655.
Kraemer M, Kremer K, Leppert R, et al. Perforating appendicitis: is it a separate disease? Eur J Surg 1999;165:473-480.
Busuttil RW, Davidson RK, Fine M, Tompkins R. Effect of prophylactic antibiotics in acute nonperforated appendicitis. A prospective, randomized, double blind clinical study. Ann Surg 1981; 194:502-508.
Asociación Mexicana de Cirugía General. Consenso Apendicitis Aguda. Veracruz;1999.
McNamara MJ, Pasquale MD, Evans SRT. Acute appendicitis and the use of intraperitoneal cultures. Surg Gynecol Obstet 1993;177: 393-397.
Camacho-Gutierrez S, Pérez-Ricarde L, Gutiérrez-Cázares Z. Frecuencia de bacterias aerobias y anaerobias en cultivos de líquido peritoneal y tejido apendicular en pacientes operados de apendicitis complicada. Cir Ciruj 1998;66:135-137.
Mosdell DM, Morris DM, Fry DE. Peritoneal cultures and antibiotic therapy in pediatric perforated appendicitis. Am J Surg 1994;167:313-316.
Neilson IR, Laberge JM, Nguyen LT, et al. Appendicitis in children: current therapeutic recommendations. J Pediatr Surg 1990;25:1113-1116.
Snelling CM, Poenaru D, Drover JW. Minimum postoperative anti-biotic duration in advanced appendicitis in children: a review. Pediatr Surg Int 2004;20:838-845.
Hoelzner DJ, Zabel DD, Zern JT. Determining duration of antibiotic use in children with complicated appendicitis. Pediatr Infect Dis J 1999;18:979-982.