2023, Number 4
Enf Infec Microbiol 2023; 43 (4)
Bloodstream infection by Burkholderia cepacia and respiratory tract co-infection by SARS-COV-2 in a neonate with neonatal minimal intervention therapy. Clinical case
Galván CR, Morales CA, Mondragón ZU, Villalobos AG, Álvarez PIJ, Solórzano SF
Language: Spanish
References: 10
Page: 165-168
PDF size: 278.68 Kb.
ABSTRACT
Burkholderia cepacia complex is a group of non-fermenting, aerobic, catalase-producing gram-negative bacilli that has been associated with serious infections in immunocompromised patients such as patients with chronic granulomatous disease and cystic fibrosis. Reports of infection by this agent in neonates are not frequent.Clinical case. Female, 30 weeks gestational age with bronchopulmonary dysplasia and depression due to anesthetics. At eight days of age she presented respiratory distress syndrome, fever and desaturation episodes requiring CPAP placement. Laboratory: C-reactive protein 30 mg/L. Blood count with leukopenia, Burkholderia cepacia growth in peripheral blood culture, sensitive to carbapenems. Meropenem was administered. He developed new febrile episodes and inadequate respiratory progress. PCR-RT for SARS-COV-2 was requested, confirming the diagnosis of horizontally acquired COVID-19. She gradually presented clinical remission, she was discharged after 48 days of extrauterine life without apparent sequelae.
Discussion. The presence of this pathogen in a neonate receiving neonatal minimal intervention therapy is extremely rare and thus highlights the complexity of neonatal care and the need for a comprehensive approach to address multiple medical conditions. In this patient, two emerging events coexisted: B. cepacia infection and SARS-COV-2 infection.
REFERENCES
Okomo, U., Senghore, M., Darboe, S., Bojang, E., Zaman,S.M.A., Hossain, M.J. et al., “Investigation ofsequential outbreaks of Burkholderia cepacia and multidrug-resistant extended spectrum β-lactamase producingKlebsiella species in a West African tertiary hospitalneonatal unit: a retrospective genomic analysis”, LancetMicrobe, 2020, 1 (3): e119-e129.