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Centro de Investigaciones Regionales Dr. Hideyo Noguchi, Universidad Autónoma de Yucatán

2023, Number 2

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Rev Biomed 2023; 34 (2)

Resistance to antibiotics of the genus Aeromonas, as an emerging opportunistic pathogen in fish and humans

Montes PDA, Baez A, Venegas B, Reyes-Luna EML, Molina-Romero D

Language: Spanish
References: 69
Page: 191-207
PDF size: 480.71 Kb.


ABSTRACT

Aeromonas is a bacteria genus reported as an emerging pathogen; due to its ability to generate infectious diseases that affect the gastrointestinal system, the circulatory system and some soft tissues of immunocompromised individuals, older adults and infants. Also, Aeromonas is an opportunistic pathogen of mammals and fish with various virulence factors. This genus proliferates in multiple environments such as soil, water, and on different hosts. This bibliographic review aims to describe the metabolic and genetic processes that give the genus Aeromonas resistance to antibiotics, the ability to form a biofilm, genes regulated by Quorum Sensing (QS), and horizontal gene transfer. In addition, it discusses some characteristics that position Aeromonas infection as a public health problem. The exhaustive review of the genus Aeromonas was carried out in the databases of the National Center for Biotechnology Information (NCBI) and the Multidisciplinary Institute of Digital Publications (MDPI) from 2017 to date and the following search criteria were considered: virulence factors, antibiotic resistance, biofilm formation, and horizontal gene transfer. The investigation indicated that Aeromonas presents several extracellular, enzymatic, and structural virulence factors; moreover, it is resistant to antibiotics such as beta-lactams, tetracyclines, and macrolides, and it has several genes that give it this resistance. Likewise, the genus Aeromonas can form biofilm, and it has three QS systems.


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