2021, Number 3
Behavior of comorbidities in mortality of patients with chronic heart failure
Language: Spanish
References: 38
Page: 1-17
PDF size: 407.22 Kb.
ABSTRACT
Introduction: Heart failure is a worldwide problem and will increase in the coming years as a result of population aging. It is associated with multiple comorbidities that may be involved in its development, contribute to the progression of the disease, or worsen the prognosis.Objective: To assess the influence of comorbidities on the mortality of patients with chronic heart failure.
Methods: A retrospective cohort study was carried out in 242 patients with a diagnosis of chronic heart failure and a mean follow-up of 5 years in the heart failure protocol consultation at Hermanos Ameijeiras Surgical Clinical Hospital. The magnitude of the association between the presence of comorbidities and mortality was determined through the use of logistic regression.
Results: The mean age was higher in deceased patients 72.12 ± 12.088 years (p = 0.003). The isolated presence of comorbidities did not show an association with mortality, but it did when more than two comorbidities coexisted. (OR: 2.91. CI: .991-8.61). A linear association was found between the number of comorbidities and mortality (p = 0.044).
Conclusion: The studied comorbidities did not show an independent association with mortality, but the sum of them did increase the risk of death in patients with heart failure.
REFERENCES
Upadhya B, Rocco M, Lewis CE, Oparil S, Lovato LC, Cushman WC, et al. Effect of intensive blood pressure treatment on heart failure events in the systolic blood pressure reduction intervention trial. Circ Heart Fail. 2017;10(4):e003613. Disponible en: https://doi.org/10.1161/CIRCHEARTFAILURE.116.003613
Agrinier N, Thilly N, Briançon S, Juillière Y, Mertes PM, Villemot JP, et al. Prognostic factors associated with 15-year mortality in patients with hospitalized systolic HF: Results of the observational community-based EPICAL cohort study. Int J Cardiol. 2017;228:940-7. Disponible en: https://doi.org/10.1016/j.ijcard.2016.11.260
Stewart S, Riegel B, Boyd C, Ahamed Y, Thompson DR, Burrell LM, et al. Establishing a pragmatic framework to optimise health outcomes in heart failure and multimorbidity (ARISE-HF): A multidisciplinary position statement. Int J Cardiol. 2016;212:1-10. Disponible en: https://doi.org/10.1016/j.ijcard.2016.03.001
Yancy CW, Jessup M, Bozkurt B, Butler J, Casey DE, Drazner MH, et al. 2013 ACCF/AHA guideline for the management of heart failure: a report of the American College of Cardiology Foundation/American Heart Association Task Force on Practice Guidelines. J Am Coll Cardiol. 2013;62(16):e147-239. Disponible en: https://doi.org/10.1161/CIR.0b013e31829e8776
Braunschweig F, Linde C, Benson C, Stahlberg M, Dahlstrom U, Lund LH. New York Heart Association functional class, QRS duration, and survival in heart failure with reduced ejection fraction: implications for cardiac resychronization therapy. Eur J Heart Fail. 2017;19:366-76. Disponible en: https://doi.org/10.1002/ejhf.563
Anguita M, Crespo MG, de Teresa E, Jiménez M, Alonso L, Muñiz J, et al. Prevalencia de la insuficiencia cardíaca en la población general española mayor de 45 años. Estudio PRICE. Rev Esp Cardiol. 2015[acceso: 14/02/2019];61:1041-94. Disponible en: Disponible en: https://www.revespcardiol.org/es-prevalencia-insuficiencia-cardiaca-poblacion-general-articulo-13126044
González JR, Alegría E, Bertoméu V, Conthe P, de Santiago A, Zsolt I. Insuficiencia cardíaca en consultas ambulatorias: comorbilidades y actuaciones diagnóstico-terapéuticas por diferentes especialistas. Estudio EPISERVE. Rev Esp Cardiol. 2014[acceso: 14/12/2018];61:611-95. Disponible en: Disponible en: https://www.revespcardiol.org/es-insuficiencia-cardiaca-consultas-ambulatorias-comorbilidades-articulo-13123067
Conde ME, Arkuch F, Formiga L, Manzano O, Aramburu Á, González MF, et al. Diferencias en función del sexo en el perfil clínico y pronóstico de pacientes con insuficiencia cardiaca. Rev Clin Esp. 2015[acceso: 22/02/2018];215(7):363-70. Disponible en: Disponible en: https://www.revclinesp.es/es-diferencias-funcion-del-sexo-el-articulo-S0014256515000892
Franco J, Formiga F, Chivite D, Manzano L, Carrera M, Arévalo JC, et al. RICA investigadors. New onset heart failure-Clinical characteristics and short-term mortality. A RICA (Spanish registry of acute heart failure) study. Eur J Intern Med. 2015;26:357-62. Disponible en: https://doi.org/10.1016/j.ejim.2015.04.008
Josa C, Sola A, Giménez I, Rubio J, Garcés V, Pérez JI. Valor pronóstico de la ratio urea/creatinina en la insuficiencia cardiaca descompensada y su relación con el daño renal agudo. Rev Clin Esp. 2018[acceso: 12/05/2019];218(5):232-40. Disponible en: Disponible en: https://medes.com/publication/135924
Kidney Disease: Improving Global Outcomes (KDIGO) CKD-MBD Update Work Group. KDIGO 2017 Clinical Practice Guideline Update for the Diagnosis, Evaluation, Prevention, and Treatment of Chronic Kidney Disease-Mineral and Bone Disorder (CKD-MBD). Kidney Int Suppl (2011). 2017;7(1):1-59. Disponible en: https://doi.org/10.1016/j.kisu.2017.04.001
Ponikowski P, van Veldhuisen DJ, Comin J, Ertl G, Komajda M, Mareev V, et al. Beneficial effects of long-term intravenous iron therapy with ferric carboxymaltose in patients with symptomatic heart failure and iron deficiency. Eur Heart J. 2015;36:657-6m. Disponible en: https://doi.org/10.1016/j.rec.2017.01.002
Pérez MD, León JL, Dueñas A, Navarro DA, de la Noval R, del Pozo H, et al. Guía Cubana de diagnóstico, evaluación y tratamiento de la hipertensión arterial. Rev Cubana Med. 2017[acceso: 14/05/2019];56. Disponible en: Disponible en: http://files.sld.cu/hta/files/2018/02/guia-Cubana-de-Diagnostic0-Evaluacion-y-Tratamiendo-de-la-HTA-2017.pdf
Franco J, Formiga F, Chivite D, Manzano L, Carrera M, Arévalo JC, et al. RICA investigators. New onset heart failure-Clinical characteristics and short-term mortality. A RICA (Spanish registry of acute heart failure) study. Eur J Intern Med. 2015;26:357-62. Disponible en: https://doi.org/10.1016/j.ejim.2015.04.008
Mogensen UM, Ersbøll M, Andersen M, Andersson C, Hassager C, Torp-Pedersen C, et al. Clinical characteristics and major comorbidities in heart failure patients more than 85 years of age compared with younger age groups. Eur J Heart Fail. 2014;13:1216-23. Disponible en: https://doi.org/10.1093/eurjhf/hfr116