2022, Number 1
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Rev Med UV 2022; 22 (1)
Cancer in COVID-19 times. Practical approach from the diagnostic process of respiratory triage
Ortiz-González J, Espinoza-Morales E, Coronel-Brizio PG
Language: Spanish
References: 68
Page: 65-90
PDF size: 360.82 Kb.
ABSTRACT
Introduction: The combined frequency of
cancer and COVID-19 is low. Cancer patients
are more susceptible to severe complications
from COVID-19. General measures to keep
COVID-19–free cancer divisions have been
adopted worldwide.
Objective: To perform
a biomedical literature review regarding the
relevant practical aspects in medical care of
cancer and COVID-19 duality, from the perspective
of an oncology center.
Material
and Methods: A review of the national and
international biomedical literature (68 selected
citations) published from February
2020 to September 2021 was carried out.
The pubMed and Hinari Health Research Access
Program databases were used to locate
and select the material. Retrospective design
studies, original articles, systematic reviews
and meta-analyzes were selected, using the
search terms: “cancer”, “triage”, “diagnosis”
and “COVID-19”.
Results: In pandemic, the
availability of cancer prevention, diagnosis
and treatment services is limited. COVID-19
respiratory triage allows prioritizing cancer
patient care. Computed tomography has high
sensitivity and low specificity for identifying
suspicious lesions. Diagnostic gold standard
for COVID-19 is RT-qPCR. COVID-19, rapid
antigen detection tests are cost-effective
in resource-limited settings. Cancer guidelines
for COVID-19 may show a low level of
evidence. Cancer treatments should not be
delayed in high priority patients.
Conclusions:
The diagnostic process of COVID-19
respiratory triage and the prioritization of
the various aspects of cancer care in the context
of a current and future pandemic, became
powerful tools to mitigate the impact
of COVID-19.
REFERENCES
Addison, D., Campbell, C. M., Guha, A., Ghosh, A. K., Dent, S. F., & Jneid, H.(2020). Cardio-Oncology in the Era of the COVID-19 Pandemicand Beyond. Journal of the American Heart Association, 9(19),e017787-e017787. doi:10.1161/JAHA.120.017787
Ai, T., Yang, Z., Hou, H., Zhan, C., Chen, C., Lv, W., . . . Xia, L. (2020). Correlationof chest CT and RT-PCR testing for coronavirus disease2019 (COVID-19) in China: a report of 1014 cases. Radiology,296(2), E32-E40.
Al‐Shamsi, H. O., Alhazzani, W., Alhuraiji, A., Coomes, E. A., Chemaly, R.F., Almuhanna, M., . . . Xie, C. (2020). A Practical Approach to theManagement of Cancer Patients During the Novel CoronavirusDisease 2019 (COVID‐19) Pandemic: An International CollaborativeGroup. The oncologist (Dayton, Ohio), 25(6), e936-e945.doi:10.1634/theoncologist.2020-0213
Bahareh Gholami, S. G., Amir Hossein Loghman, Behzad Khodaei, SiminSeyedpour, Nasrin Seyedpour, et al. (2021). Clinical andLaboratory Predictors of Severity, Criticality, and Mortality inCOVID-19: A Multisystem Disease. In S. N. S. AG (Ed.), CoronavirusDisease- COVID-19 (Vol. 1318, pp. 369-402.).
Borghesi, A., & Maroldi, R. (2020). COVID-19 outbreak in Italy: experimentalchest X-ray scoring system for quantifying and monitoringdisease progression. La radiologia medica, 125(5), 509-513.
Brunello, A., Galiano, A., Finotto, S., Monfardini, S., Colloca, G., Balducci,L., & Zagonel, V. (2020). Older cancer patients and COVID‐19outbreak: Practical considerations and recommendations. Cancermedicine (Malden, MA), 9(24), 9193-9204. doi:10.1002/cam4.3517
Cerutti, F., Burdino, E., Milia, M. G., Allice, T., Gregori, G., Bruzzone, B.,& Ghisetti, V. (2020). Urgent need of rapid tests for SARS CoV-2antigen detection: Evaluation of the SD-Biosensor antigen testfor SARS-CoV-2. Journal of Clinical Virology, 132, 104654.
Chamorro, E. M., Tascón, A. D., Sanz, L. I., Vélez, S. O., & Nacenta, S. B.(2021). Diagnóstico radiológico del paciente con COVID-19. Radiologia,63(1), 56-73.
Chen, T., Wu, D., Chen, H., Yan, W., Yang, D., Chen, G., . . . Wang, H. (2020).Clinical characteristics of 113 deceased patients with coronavirusdisease 2019: retrospective study. Bmj, 368.
Constantinou, C., Kolokotroni, O., Mosquera, M. C., Heraclides, A., Demetriou,C., Karayiannis, P., . . . Charalambous, A. (2020). Developinga holistic contingency plan: Challenges and dilemmas for cancerpatients during the COVID‐19. Cancer medicine (Malden, MA),9(17), 6082-6092. doi:10.1002/cam4.3271
Cortés-Meza, H. M., Arellano-Hernández, N., Colín-Martínez, T., Bañuelos-Huerta, R., Bravo-Gutiérrez, J. V., Loria-Castellanos, J., . . . Zapata-Centeno, I. (2020). Respiratory triage. Medicina Interna deMéxico, 36(S2), 18-22.
Delon-Huerta N, G. C. (2021). Enfoque imagenológico ante el COVID-19.BMCAE, 1, 18-24.
Ehni, H. J., Wiesing, U., & Ranisch, R. (2021). Saving the most lives—Acomparison of European triage guidelines in the context of theCOVID‐19 pandemic. Bioethics, 35(2), 125-134. doi:10.1111/bioe.12836
Eleftheriou, I., Dasoula, F., Dimopoulou, D., Lebessi, E., Serafi, E., Spyridis,N., & Tsolia, M. (2021). Real‐life evaluation of a COVID‐19 rapidantigen detection test in hospitalized children. Journal of medicalvirology, 93(10), 6040-6044. doi:10.1002/jmv.27149
European Society for Medical Oncology. Cancer patient managementduring the COVID-19 pandemic. 2020. (2020). Retrieved fromhttps://www.esmo.org/guidelines/cancer-patient-management-during-the-covid-19-pandemic.
Fasola, G., Pelizzari, G., Zara, D., Targato, G., Petruzzellis, G., Minisini, A.M., . . . Fanin, R. (2021). Feasibility and Predictive Performance ofa Triage System for Patients with Cancer During the COVID‐19Pandemic. The oncologist (Dayton, Ohio), 26(4), e694-e703.doi:10.1002/onco.13706
Fenollar, F., Bouam, A., Ballouche, M., Fuster, L., Prudent, E., Colson, P.,. . . Raoult, D. (2020). Evaluation of the Panbio Covid-19 rapidantigen detection test device for the screening of patients withCovid-19. Journal of clinical microbiology, 59(2), e02589-02520.
Garg, P. K., Kaul, P., Choudhary, D., Turaga, K. K., Singh, M. P., Tiwari, A.R., . . . Yendamuri, S. (2020). Discordance of COVID‐19 guidelinesfor patients with cancer: A systematic review. J Surg Oncol,122(4), 579-593. doi:10.1002/jso.26110
Gonçalves, B. T., & Baiocchi, G. (2021). Telemedicine and cancer researchduring the COVID‐19 pandemic. J Surg Oncol, 123(1),359-360. doi:10.1002/jso.26254
GongJ, O. J., & Qiu, X. (2020). A tool to early predict severe corona virusdisease 2019 (COVID-19): a multicenter study using the risknomogram in Wuhan and Guangdong, China. Clin Infect Dis,71(15), 833-840.
Gosain, R., Abdou, Y., Singh, A., Rana, N., Puzanov, I., & Ernstoff, M. S.(2020). COVID-19 and cancer: a comprehensive review. Currentoncology reports, 22, 1-15.
Guo, L., Ren, L., Yang, S., Xiao, M., Chang, D., Yang, F., . . . Xiao, Y. (2020).Profiling early humoral response to diagnose novel coronavirusdisease (COVID-19). Clinical Infectious Diseases, 71(15),778-785.
Hasson, S. P., Waissengrin, B., Shachar, E., Hodruj, M., Fayngor, R., Brezis,M., . . . Wolf, I. (2021). Rapid Implementation of TelemedicineDuring the COVID‐19 Pandemic: Perspectives and Preferencesof Patients with Cancer. The oncologist (Dayton, Ohio), 26(4),e679-e685. doi:10.1002/onco.13676
Herrera-Almanza, L., Hernández-Martínez, A., Roldan-Tabares, M. D.,Hernández-Restrepo, F., Thowinson-Hernández, M. C., Coronado-Magalhães, G., . . . Martínez-Sánchez, L. M. (2022). El triagecomo herramienta de priorización en los servicios de urgencias.Medicina Interna de México, 38(2), 322-334.
Herrera-Sánchez, D. A., & Rivera-Alvarado, K. L. (2020). Diseño deltriage respiratorio COVID-19. Entrevistando a Tania Colín Martínez.Revista Alergia México.
Indini, A., Cattaneo, M., Ghidini, M., Rijavec, E., Bareggi, C., Galassi,B., . . . Grossi, F. (2021). Triage process for the assessmentof coronavirus disease 2019‐positive patients with cancer:The ONCOVID prospective study. Cancer, 127(7), 1091-1101.doi:10.1002/cncr.33366
Jagtap, V. S., More, P., & Jha, U. (2020). A review of the 2019 novel coronavirus(COVID-19) based on current evidence.
Jefferson RdS S, T. A. (2020). Clinical and Laboratory Diagnosis of SARS.CoV-2, the Virus Causing COVID-19. Infect Dis ACS, 6(9), 2319-2336.
Lee, L. Y., Cazier, J. B., Starkey, T., Turnbull, C., Team, U. C. C. M. P., Kerr,R., & Middleton, G. (2020). COVID-19 mortality in patients withcancer on chemotherapy or other anticancer treatments: a prospectivecohort study. The Lancet, 395(10241), 1919-1926.
Liang, W., Guan, W., Chen, R., Wang, W., Li, J., Xu, K., . . . Liang, H. (2020).Cancer patients in SARS-CoV-2 infection: a nationwide analysisin China. The lancet oncology, 21(3), 335-337.
Liu, C., Zhao, Y., Okwan-Duodu, D., Basho, R., & Cui, X. (2020). COVID-19in cancer patients: risk, clinical features, and management. Cancerbiology & medicine, 17(3), 519.
Ma, J., Yin, J., Qian, Y., & Wu, Y. (2020). Clinical characteristics and prognosisin cancer patients with COVID-19: A single center's retrospectivestudy. The Journal of infection.
Mallett S, J. A., GRaziadio S. (2020). At what times during infection isSARS CoV-2 detectable and no longer detectable using RT-PCR.based tests? BMC Medicine, (18), 346.
Manna, S., Wruble, J., Maron, S. Z., Toussie, D., Voutsinas, N., Finkelstein,M., . . . Jacobi, A. (2020). COVID-19: a multimodality review ofradiologic techniques, clinical utility, and imaging features. Radiology:Cardiothoracic Imaging, 2(3), e200210.
Martínez-Saíd, H. (2021). Los retos por venir en la oncología mexicanapara 2021, de la pandemia a la sindemia. Gaceta mexicana de oncología,20(1), 1-2.
Matsuda, E. M., Campos, I. B., Oliveira, I. P., Colpas, D. R., Carmo, A. M. d.S., & Brígido, L. F. d. M. (2021). Field evaluation of COVID‐19 antigentests versus RNA based detection: Potential lower sensitivitycompensated by immediate results, technical simplicity, and lowcost. Journal of medical virology, 93(7), 4405-4410. doi:10.1002/jmv.26985
Mendoza-Popoca, C. Ú., & Suárez-Morales, M. (2020). Reconversiónhospitalaria ante la pandemia de COVID-19. Revista Mexicana deAnestesiología, 43(2), 151-156.
Nussbaumer-Streit, B., Mayr, V., Dobrescu, A. I., Chapman, A., Persad, E.,Klerings, I., . . . Zachariah, C. (2020). Quarantine alone or in combination with other public health measures to control COVID‐19:a rapid review. Cochrane Database of Systematic Reviews(9).
Ontario., O. H. C. C. (March 10 2020). Pandemic planning clinical guidelinefor patients with cancer. : https://www.accc-cancer.org/docs/documents/cancerprogram-fundamentals/oh-cco-pandemic-planning-clinicalguideline_final_2020-03-10.pdf?sfvrsn=d2f04347_2.
Organisation, E. C. (2020). Statement on COVID-19 from the EuropeanCancer Organisation’s Board of Directors, 17th March 2020. . Retrievedfrom https://www.europeancancer.org/resources/29:-news-statement-on-covid-19-from-the-european-cancer-organisation-s-board-of-directors.html
Penagos, J. C. G., Robledo, R. S., Moralesa, A. P. H., Piedra, L. E. P., Farías-Contreras,J. P., Rojas-Varela, R., . . . Juárez-Hernández, F. (2020). Hallazgostomográficos en afectación pulmonar por COVID-19, experienciainicial en el Instituto Nacional de Enfermedades RespiratoriasIsmael Cosío Villegas, Ciudad de México. NCT Neumología yCirugía de Tórax, 79(2), 71-77.
Prasad Meena, J., Kumar Gupta, A., Tanwar, P., Ram Jat, K., Mohan Pandey,R., & Seth, R. (2021). Clinical presentations and outcomes of childrenwith cancer and COVID-19: A systematic review. Pediatricblood & cancer, e29005-e29005. doi:10.1002/pbc.29005
Prokop, M., Van Everdingen, W., van Rees Vellinga, T., Quarles van Ufford,H., Stöger, L., Beenen, L., . . . Schaefer-Prokop, C. (2020). CO-RADS:a categorical CT assessment scheme for patients suspected ofhaving COVID-19—definition and evaluation. Radiology, 296(2),E97-E104.
Ramani, V. K., & Naik, R. (2021). A narrative review of the pathophysiologyof COVID‐19 infection among cancer patients: Current evidenceand research perspectives. Health Science Reports, 4(1), e237.
Ramaswamy, A., Nayak, L., Roy Moulik, N., Sengar, M., Chinnaswamy, G.,Jobanputra, K., . . . Prabhash, K. (2020). COVID‐19 in cancer patientson active systemic therapy – Outcomes from LMIC scenariowith an emphasis on need for active treatment. Cancer medicine(Malden, MA), 9(23), 8747-8753. doi:10.1002/cam4.3423
Rubin, G. D., Ryerson, C. J., Haramati, L. B., Sverzellati, N., Kanne, J. P.,Raoof, S., . . . Martin, I. B. (2020). The role of chest imaging in patientmanagement during the COVID-19 pandemic: a multinationalconsensus statement from the Fleischner Society. Radiology,296(1), 172-180.
Salinas-Aguirre, J., Sánchez-García, C., Rodríguez-Sanchez, R., Rodríguez-Muñoz, L., Díaz-Castaño, A., & Bernal-Gómez, R. (2021).Características clínicas y comorbilidades asociadas a mortalidaden pacientes con COVID-19 en Coahuila (México). Revista ClínicaEspañola.
Salud, O. M. d. l. (27 de mayo 2020). Manejo Clínico de la COVID-19. Orientacionesprovisionales. (WHO/2019-nCoV/clinical/2020.5).
Salud, S. d. (2021). Lineamiento estandarizado para la vigilancia epidemiológicay por laboratorio de la enfermedad respiratorioa viral.Enero de 2021. México Retrieved from www.gob.mx/salud
Salud, S. d. (Versión 5 de abril 2020). Lineamiento de Reconversión Hospitalaria.México Retrieved from https://coronavirus.gob.mx/wp-content/uploads/2020/04/Documentos-Lineamientos-Reconversion-Hospitalaria.pdf
Salunke, A. A., Nandy, K., Pathak, S. K., Shah, J., Kamani, M., Kottakota, V.,. . . Pandya, S. (2020). Impact of COVID -19 in cancer patients onseverity of disease and fatal outcomes: A systematic review andmeta-analysis. Diabetes & metabolic syndrome clinical research &reviews, 14(5), 1431-1437. doi:10.1016/j.dsx.2020.07.037
Shan, F., Gao, Y., Wang, J., Shi, W., Shi, N., Han, M., . . . Shi, Y. (2020). Abnormallung quantification in chest CT images of COVID-19 patientswith deep learning and its application to severity prediction. Medicalphysics (Lancaster). doi:10.1002/mp.14609
Shi, H., Han, X., Jiang, N., Cao, Y., Alwalid, O., Gu, J., . . . Zheng, C. (2020).Radiological findings from 81 patients with COVID-19 pneumoniain Wuhan, China: a descriptive study. The Lancet infectiousdiseases, 20(4), 425-434.
Soto-Pérez-de-Celis, E., Arrieta, O., Bargalló-Rocha, E., Campos-Gómez,S., Chávarri-Guerra, Y., Chávez-Nogueda, J., . . . Martínez-Said, H.(2021). Recomendaciones de la Sociedad Mexicana de Oncologíapara la vacunación contra Covid-19 en personas con cáncer enMéxico. Salud Pública de México.
Spiezia, L., Boscolo, A., Poletto, F., Cerruti, L., Tiberio, I., Campello, E., . .. Simioni, P. (2020). COVID-19-related severe hypercoagulabilityin patients admitted to intensive care unit for acute respiratoryfailure. Thrombosis and haemostasis, 120(6), 998.
Subbiah, S., Hussain, S. A., & Samanth Kumar, M. (2020). Managingcancer during COVID pandemic - Experience of a tertiarycancer care center. European journal of surgical oncology.doi:10.1016/j.ejso.2020.09.027
Tan, L., Wang, Q., Zhang, D., Ding, J., Huang, Q., Tang, Y.-Q., . . . Miao,H. (2020). Lymphopenia predicts disease severity of COVID-19: a descriptive and predictive study. Signal transductionand targeted therapy, 5(1), 1-3.
Terpos, E., Ntanasis‐Stathopoulos, I., Elalamy, I., Kastritis, E., Sergentanis,T. N., Politou, M., . . . Dimopoulos, M. A. (2020). Hematologicalfindings and complications of COVID‐19. Americanjournal of hematology, 95(7), 834-847. doi:10.1002/ajh.25829
Tian, Y., Qiu, X., Wang, C., Zhao, J., Jiang, X., Niu, W., . . . Zhang, F.(2021). Cancer associates with risk and severe events ofCOVID‐19: A systematic review and meta‐analysis. Internationaljournal of cancer, 148(2), 363-374. doi:10.1002/ijc.33213
Vaduganathan, M., Vardeny, O., Michel, T., McMurray, J. J., Pfeffer,M. A., & Solomon, S. D. (2020). Renin–angiotensin–aldosteronesystem inhibitors in patients with Covid-19. NewEngland Journal of Medicine, 382(17), 1653-1659.
Villain, P., Carvalho, A. L., Lucas, E., Mosquera, I., Zhang, L., Muwonge,R., . . . for the, I. C. I. S. G. (2021). Cross-sectional surveyof the impact of the COVID-19 pandemic on cancer screeningprograms in selected low- and middle-income countries:Study from the IARC COVID-19 impact study group.International journal of cancer. doi:10.1002/ijc.33500
Wan, S., Yi, Q., Fan, S., Lv, J., Zhang, X., Guo, L., . . . Yi, Z. (2020). Relationshipsamong lymphocyte subsets, cytokines, and thepulmonary inflammation index in coronavirus (COVID‐19)infected patients. British journal of haematology, 189(3),428-437.
Wasim Khan, S. A., Farah Deeba, Ayesha Tazeen, Nasir, & Salam, I.H. N., et al. (2021). Global Epidemiology and Transmissionof COVID-19. In S. Parveen (Ed.), The COVID-19 Pandemic:Epidemiology, Molecular Biology and Therapy (pp. 78-102).New Delhi India: Bentham Science Publishers LTD.
Wölfel, R., Corman, V. M., Guggemos, W., Seilmaier, M., Zange, S., Müller,M. A., . . . Rothe, C. (2020). Virological assessment of hospitalizedpatients with COVID-2019. Nature, 581(7809), 465-469.
Xia, Y., Jin, R., Zhao, J., Li, W., & Shen, H. (2020). Risk of COVID-19 forcancer patients. Lancet Oncol, 21(4).
Xiang, F., Wang, X., He, X., Peng, Z., Yang, B., Zhang, J., . . . Li, H. (2020).Antibody detection and dynamic characteristics in patientswith coronavirus disease 2019. Clinical Infectious Diseases,71(8), 1930-1934.
Yu, J. C., Khodadadi, H., Malik, A., Davidson, B., Salles, É. d. S. L., Bhatia,J., . . . Baban, B. (2018). Innate immunity of neonates and infants.Frontiers in immunology, 9, 1759.
Zhang, L., Zhu, F., Xie, L., Wang, C., Wang, J., Chen, R., . . . Chen, Y. (2020).Clinical characteristics of COVID-19-infected cancer patients: aretrospective case study in three hospitals within Wuhan, China.Annals of oncology, 31(7), 894-901.