2022, Number 3
<< Back Next >>
Rev Med UAS 2022; 12 (3)
Analgesic efficiency of 2% ropivacaine + fentanyl vs 2% ropivacaine + morphine by peridural administration in patients with contaminated wound in the immediate postoperative period
Torres-Escobar NJ, Prince-Angulo SA, Peraza-Garay FJ, Canizales-López M
Language: Spanish
References: 15
Page: 167-174
PDF size: 130.07 Kb.
ABSTRACT
Objectives: To determine which combination is more effective for the control of pain and hemodynamic behavior in the postoperative
period in patients undergoing cleaning of contaminated surgical wound in the lower part of the body.
Material and Methods: A controlled,
prospective, longitudinal, comparative, randomized and double-blind clinical trial was conducted in adult patients with a contaminated
lower-body wound, 2 groups with a total of 87 patients, 40 patients with ropivacaine + fentanyl 100mcg (RF Group) vs 2%
ropivacaine + morphine 2mg( RM Group) by peridural route. During the postsurgical period, heart rate, blood pressure, respiratory
rate, oxygen saturation, the presence or absence of pruritus, nausea and / or vomiting, visual analogue scale (VAS) were monitored
at the first hour, 2 and 4 hours after surgical cleaning.
Results: For the RF group (40) and RM (47), in the pain evaluation with the
EVA scale, al the first hour with a zero score, the group RF 20 (50%) and the RM 47 group (100%) p = ‹0.000. At 2 hours with a zero
score, group RF 6 (15%) and RM 35 (74.5%) p = ‹0.000. At 4 hours on zero score, group RF 4 (10%) and RM 21 (44.7%) p = ‹0.000.
Conclusion: The RM group had better analgesia than the RF group.
REFERENCES
Erazo MA, Pérez L, Colmenares CC, ÁlvarezH, Suárez I, Mendivelso F. Prevalencia ycaracterización del dolor en pacientes hospitalizados.Rev Soc Esp Dolor. 2015;22(6):241–8.
Fernández L. Valoración de las escalas dedolor en pacientes con ventilación mecánicaen Unidad de Cuidados Intensivos [Tesis deLicenciatura]. Coruña: Universidad de Coruña;2014.
Robleda G, Roche-Campo F, Membrilla-Martínez L, Fernández-Lucio A, Villamor-Vázquez M, Merten A, et al. Evaluación deldolor durante la movilización y la aspiraciónendotraqueal en pacientes críticos. Med Intensiva.2016; 40(2):96–104.
Bernal C, Pérez M, Forastero A, Serra C,Álamo JM, Docobo F. Dolor agudo postoperatorio.Mecanismos neurofisiológicos. CirAndal. 20016; 17: 20-26.
Pérez AG, Sánchez M, Bautista DC, MendosaR, Fragoso L, Velarde LT, et al. Prevalenciade infección de herida quirúrgica, causasy resistencia a los fármacos en el HospitalGeneral de Zona núm. 2 del IMSS, SanLuis Potosí. Rev Espec Méd-Quirúrgicas.2012; 17(4):261–265.
Reyes RD, Navarro JR, Camargo HA. Anestesiaespinal para cesárea con bupivacainapesada al 0.5 % 7 mg más fentanil 20 mcgvs bupivacaina pesada al 0.5 % 9 mg. RevCol Anest. 2012. 30(3): 1-12.
Mugabure B, Echaniz E, Marín M. Physiologyand clinical pharmacology of epiduraland intrathecal opioids. Rev Soc Esp Dolor2005; 12: 33-45.
Gupta A, Singh N. Pharmacology in anesthesiapractice. [Dissertation] Oxford: OxfordUniversity Press; 2013.
Blanco B, García J, García-Agua S. Resultadosen salud y eficiencia del fentanilo intranasalen pectina en el dolor irruptivo en lapráctica clínica habitual. Rev Soc Esp Dolor.2013;20(5):221–9.
Wilkes DM, Orillosa SJ, Hustak EC, WilliamsCG, Doulatram GR, Solanki DR, et al. Efficacy,Safety, and Feasibility of the MorphineMicrodose Method in Community-Based Clinics.Pain Med. 2017; 19(9):1782-1789.
Dahl JB, Jeppesen IS, Jørgensen H, WetterslevJ, Møiniche S. Intraoperative andpostoperative analgesic efficacy and adverseeffects of intrathecal opioids in patientsundergoing cesarean section with spinalanesthesia: a qualitative and quantitativesystematic review of randomized controlledtrials. Rev Anestesiol.1999; 91(6):1919-27.
Sayed A, Olivazzi A, Corvalán S, SantiagoG, Béjar J, Díaz A. Estudio Comparativo"Ropivacaína-Fentanilo en infusión epiduralversus Morfina intratecal para analgesia posoperatoriaen cirugía mayor de abdomen.Update in Anaesth. 2008; 21(2): 3-5.
Santiago RG, Posi G, Ogas M, Dicuatro N,González Vélez M. Uso comparativo debupivacaína vs. ropivacaína peridural asociadosa fentanilo en cesárea. Rev ArgentAnestesiol. 2002;60(4):209–26.
Ríos AR, Sifuentes G. Eficacia de la analgesiapor vía peridural con ropivacaina adicionadacon fentanilo comparada con ropivacainasimple en pacientes postoperadas dehisterectomía total abdominal. (Tesis). UniversidadAutónoma del Estado de México.Toluca: 2013.
Domínguez F, Ortiz G, Guerro F, Lagarda J.Nalbfina SP más ropivacaína versus fentanilomás ropivacaína peridural mediantebomba de infusión elastomérica para manejode dolor postoperatorio en pacientessometidas a histerectomía total abdominal.Anest Analg Reanim. 2012; 25(1):7–12.