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Órgano Oficial del Instituto de Ciencias de la Salud, Hospital Escuela y Facultad de Medicina-Xalapa

2021, Number 1

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Rev Med UV 2021; 21 (1)

Clinical overview of COVID-19 behavior in Puebla: Prevalence and Severity

Cortés-López YI, López-Paz I, Marín-Márquez G, Albavera-Peña JD, Montiel-Jarquín ÁJ, Parada-Jiménez JJ

Language: Spanish
References: 32
Page: 39-56
PDF size: 557.60 Kb.


ABSTRACT

On February 27, the first case of COVID-19 was confirmed in Mexico, a disease caused by the SARS Cov-2 virus. Until August 7, data from the John Hopkins University show 201 million infected, while in Mexico 2.94 million infected in the world, causing 4.27 million deaths. Objective: To describe the clinical behavior and characteristics associated with severity/ mortality in COVID-19. Methods: Data from 280 patients confirmed to COVID-19 by RT PCR were obtained, with moderate and severe clinical expressions that warranted hospital management at the High Specialty Medical Unit in Puebla from March 1 to June 30, 2020. Results: The mean age was 54.31 years and 63.57% (n = 178) were men. The comorbidities found were overweight: 49.28% (n = 138), obesity: 35% (n = 98), systemic arterial hypertension: 25.35% (n = 71), diabetes mellitus: 24.64% (n = 69), kidney transplantation: 5% (n = 12). Respiratory symptoms were reported in 86.07% (n = 241). Of the total number of patients, only 15.71% (44) required ventilatory mechanical assistance. The risk factors associated with death were Systemic Arterial Hypertension (SAH) OR = 5.31 (95% CI 2.14- 12.75), Male sex OR = 4.77 (95% CI 1.65-13.84), Mechanical-Ventilatory Assistance (AMV) OR = 3.2 (95% CI 1.3-7.86), transplantation OR= 102 (95% CI 14.91-699) and there was a protective factor called respiratory symptoms OR = 0.12 (95% CI 0.05-0.3). Conclusion: COVID 19 is more prevalent in men. The mortality rate was 17.5% (49/280). The risk factors for mortality were SAH, male sex, AMV, Transplantation and finally, respiratory symptom was a protective factor.


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