2020, Number 4
<< Back Next >>
Rev Cub Oftal 2020; 33 (4)
Clinical and epidemiological characterization of pseudoexfoliation syndrome
Sánchez AL, Rodríguez SB, Méndez DAM, Cárdenas CD, Nafeh MMI
Language: Spanish
References: 20
Page: 1-17
PDF size: 487.66 Kb.
ABSTRACT
Objective:
Determine the clinical and epidemiological characteristics of pseudoexfoliation syndrome.
Methods:
A study was conducted of 109 eyes of 55 patients attending the Ocular Microsurgery Center and Glaucoma Service at Ramón Pando Ferrer Cuban Institute of Ophthalmology from July 2016 to September 2017. Characterization was based on determinations made by gonioscopy, tonometry, pachymetry, endothelial microscopy, funduscopy and visual acuity measurement.
Results:
Mean age was 74.6 years, with a predominance of the male sex (60%), white skin (78.2%) and frequent antecedents of vascular disease, particularly arterial hypertension (65.5%). All the patients had cataract, which was predominantly bilateral and nuclear in 92.7%. In all cases the chamber angle was open, whereas intraocular pressure was high in 36.4%. 56.4% of the patients had glaucoma, which was more commonly unilateral (38.2%). Regarding the corneal endothelium, cellularity was reduced in 40%, with polymegethism (58.2%) and pleomorphism (72.7%).
Conclusion:
No relationship was found between corneal alterations, age and intraocular pressure, and the presence of pseudoexfoliative material.
REFERENCES
Rey Iglesias A. Glaucoma pseudoexfoliativo. Gaceta. 2014 [acceso: 02/11/2017]; (492):[aprox. 6 p.]. Disponible en: https://asociaciondoce.files.wordpress.com/2015/12/cientifico1-2.pdf
Urrutia-Breton IP. Síndrome de pseudoexfoliación. Rev Mex Oftalmol. 2009 [acceso: 02/11/2017];83(2):[aprox. 7 p.]. Disponible en: http://www.medigraphic.com/pdfs/revmexoft/rmo-2009/rmo092a.pdf
Govetto A, Lorente R, Vázquez de Parga P, Rojas L, Moreno C, Lagoa F, Lorente B. Frequency of pseudoexfoliation among patients scheduled for cataract surgery. J Cataract Refract Surg. 2015 [acceso: 22/07/2017];41(6):2.
Kahn HA, Leibowitz HM, Ganley JP, Kini MM, Colton T, Nickerson RS, et al. The Framingham Eye Study. I. Outline and major prevalence findings. Am J Epidemiol. 1977;106:17-32.
Batur M, Seven E, Tekin S, Yasar T. Anterior Lens Capsule and Iris Thicknesses in Pseudoexfoliation Syndrome. Cur Eye Res. 2017 [acceso: 02/11/2017];42(11):1445-9. Disponible en: https://pubmed.ncbi.nlm.nih.gov/28910163/
Sainz Gómez C, Moreno-Montañés J, Escudero Berasategui JM, Sádaba Echarri LM, Fernández Hortelano A, García Layana A. Prevalencia y factores de riesgo del síndrome pseudoexfoliativo en una población institucionalizada en Navarra. Arch Soc Esp Oftalmol. 2003[acceso: 02/11/2017];78(7):[aprox. 5 p.]. Disponible en: http://scielo.isciii.es/scielo.php?script=sci_arttext&pid=S0365-66912003000700007&lng=es
Ariaga M, Nivean M, Utkarsha P. Pseudoexfoliation Syndrome. J Curr Glaucoma Pract. 2013 [acceso: 02/11/2017];7(3):118-20. Disponible en: https://pubmed.ncbi.nlm.nih.gov/26997794/
Ritch R, Schlötzer-Schrehardt U. Exfoliation syndrome. Surv Ophthalmol. 2001;45(4):265-315.
Tanhehco T, Chen SH. Pseudoexfoliation syndrome and cataract surgery. Int Ophthalmol Clin. 2010;50(1):[aprox. 12 p.]. DOI: http://dx.doi.org/10.1097/iio.0b013e3181c5719c
Romero-Aroca P, Masip-Serra R, Martínez-Salcedo I, Salvat-Serra M, Fernández-Ballart J, Bautista-Pérez A. High prevalence of pseudoexfoliation syndrome and its complications in Tarragona in Northeast Spain. Eur J Ophthalmol. 2011;21(5):580-8.
González Rodríguez-Sobrón JC. Análisis epidemiológico y de las características pre, intra y posquirúrgicas en nuestro medio [Tesis Doctoral]. Universidad De Cantabria, Facultad De Medicina, Departamento De Cirugía Catarata Y Síndrome Pseudoexfoliativo; 2016.
Shimizu K. Prevalence of exfoliation syndrome in the Japanese. Acta Ophthalmol. 1988;184(Suppl.):112-5.
Konstas AGP. Epidemiology of exfoliation syndrome. J Glauc. 2018 [acceso: 04/11/2020];27:4-11. Disponible en: https://journals.lww.com/glaucomajournal/FullText/2018/07001/Epidemiology_of_Exfoliation_Syndrome.2.aspx
Mitchell P. The relationship between glaucoma and pseudoexfoliation: The Blue Mountains Eye Study. Arch Ophthalmol. 1999;117(10):1319-24.
Moreno-Montañés J. El síndrome y el glaucoma pseudoexfoliativo. Pamplona: EUNSA; 1995.
Puska PM. Unilateral exfoliation syndrome: conversion to bilateral exfoliation and to glaucoma -a prospective 10 year follow-up study. J Glauc. 2002;11:517-24.
Plateroti P, Plateroti AM, Abdolrahimzadeh A, Scuderi G. Pseudoexfoliation syndrome and pseudoexfoliation glaucoma: A review of the literature with updates on surgical management. J Ophthalmol. 2015 [acceso: 04/11/2020];2015:370371. Disponible en: https://www.hindawi.com/journals/joph/2015/370371/
Tomas ZBT, Zalawsky R. Mariak Z. Evaluation of the endotelial cell density and central corneal thickness in pseudoexfoliation síndrome and pseudoexfoliation glaucoma. J Ophthalmol. 2014 [acceso: 04/11/2020];2014:123683. Disponible en: https://www.hindawi.com/journals/joph/2014/123683/
Juan-Marcos L, Cabrillo-Estévez L, Escudero-Domínguez FA, Sánchez-Jara A, Hernández G. Morphometric changes of corneal endothelial cells in pseudoexfoliation syndrome and pseudoexfoliation glaucoma. Arch Soc Esp Oftalmol. 2013;(88):439-44.
Drolsum L. Pseudoexfoliation syndrome and extracapsular cataract extraction. Acta Ophthalmol. 1993;71(6):765-70.