Covarrubias-Gómez A, Silva-Jiménez A, Nuche-Cabrera E, Téllez-Isaías M

Language: Spanish
References: 69
Page: 231-239
PDF size: 136.77 Kb.

ABSTRACT

An estimated 2 million births take place in Mexico every year; this number suggests the frequency with which obstetric postoperative analgesia is used. For this reason, the management of postoperative analgesia in childbirth is not restricted to the anesthesiologist, and it is possible that analgesic drugs might interact with both the mother and the newborn. Pain relief in obstetric care has given rise to controversies and discrepancies which limited its use in the past. Nowadays, it is generally accepted that analgesic drug management of women in pain must begin when the patient requests it. This concept had prompted the use of various postoperative analgesic techniques. However, little is known about the effect upon the newborn of analgesic drugs present in mother’s milk. The primary objective of this paper is to consider some important aspects about the historical background of obstetric analgesia, the mechanisms of pain generation, the use of therapeutic strategies, and the pharmacologic safety of analgesic drugs, in light of published evidence.

REFERENCES

1. Cambridge Advanced Learner´s Dictionary. Cambridge University Press. 2003.

2. Diccionario enciclopédico University de términos médicos. Interamericana. México. 1981.

3. Harper D. Online etymology dictionary. www.etymonline.com; 2001.

4. Merskey H. Pain terms: a list with definitions and notes on usage. Recommended by the Subcommittee on Taxonomy. Pain 1979;6:249–52.

5. Merskey H, Bogduk N. Classification of chronic pain. Second edition. IASP PRESS. Seattle 1994:209-214.

6. William C. Pain relief during labor. New Eng J Med 2005;352:718-720.

7. Wickwire J, Gross JB. From preop to postop: Cesarean delivery from the anesthesiologist pint of view. Clin Obstet Gynecol 2004;47:299-316.

8. Lowe NK. The nature of pain. Am J Obstet Gynecol 2002;186:S16-S24.

9. Laurie S, Glezerman M. The history of cesarean technique. Am J Obstet Gynecol 2003;189:1803-1806.

10. SSA. Boletín de información estadística. Daños a la salud. Volumen II. No. 18-21. Mexico, D. F.

11. Eltzsching HK, Lieberman ES, Camann WR. Medical progress: regional anesthesia and analgesia for labor and delivery. New Eng J Med 2003;348:319-332.

12. Millan MJ. The induction of pain: An integrative review. Progress Neurobiol 1999;57:1-164.

13. Whilder-Smith CH, Hill L, Dyer RA, Torr G, Coetzee E. Postoperative sensation and pain after cesarean delivery. Anesth Analg 2003;97:526-533.

14. Alexander JM, Sharma SK, McIntire DD, Wiley J, Leveno KJ. Intensity of labor pain and cesarean delivery. Anesth Analg 2001;92:1524-1528.

15. Hess PE, Pratt SD, Soni AK, Sarna MC, Oriol NE. An association between severe labor pain and cesarean delivery. Anesth Analg 2000;90:881-6.

16. Sahisto T, et al. Reduced pain tolerance during and after pregnancy in women suffering from fear of labor. Pain 2001;93:123-127.

17. Saisto T, Kaaja R, Ylikorkala O, Halmesmaki E. Factors associated with fear of delivery in second pregnancies. Obstet Gynecol 1999;94:679-682.

18. Leung AY. Postoperative pain management in obstetric anesthesia: A new challenges. J Clin Anesth 2004;16:57-65.

19. Kuczkowisky KM. Postoperative pain control in the parturient: New challenges (and their solutions). J Clin Anesth 2004;16:1-3.

20. Parker RK. Postoperative analgesia: systemic techniques. In: Chestnut DH, ed. Obstetric Anesthesia: Principles and Practice. St. Louis. Mosby. 1999:509–20.

21. Sinatra RS, Ayoub CM. Postoperative analgesia: epidural and spinal techniques. In: Chestnut DH, ed. Obstetric Anesthesia: Principles and Practice. St. Louis. Mosby. 1999:521–55.

22. Shinya I. Drug therapy: Drug therapy for the breast-feeding women. N Eng J Med 2001;343:118-126.

23. American Academy of Pediatrics, Work Group on Breastfeeding. Breastfeeding and the use of human milk. Pediatrics 1997;100:1035-1039.

24. World Health Organization. Cancer pain relief. 2nd ed. Geneva: WHO Office of publication; 1996.

25. Management of acute of pain: A practical guide, Task Force on Acute Pain, International Associate for Study of Pain. Ed. Seattle IASP, 1992.

26. National Health and Medical Research Council. Acute pain management: scientific evidence. Australia. 1999.

27. McQuay H. Opioids in pain management. Lancet 1999;353:2232-2239.

28. Tanioko T, Nakatani Y, Semmyo N, et al. Molecular identification of cytosolic prostaglandin E2 synthase that is functionally coupled with cyclooxygenase-1 in immediate prostaglandin E2 biosynthesis. J Biol Chem 2000;42:32775-32779.

29. Murakami M, Naraba H, Tanioka T, et al. Regulation of prostaglandin E2 biosynthesis by inducible membrane-associated prostaglandin E2 synthase that acts in concert with cyclooxygenase-2. J Biol Chem 2000;42:32783-32788.

30. Funk CD. Prostaglandins and leukotrienes: advances in eicosanoid biology. Science 2001;249:1871-1879.

31. Jansen N, Genta MS. The effects of immunosuppressive and anti-inflammatory medications on fertility, pregnancy, and lactation. Arch Intern Med 2000;160:610-619.

32. Turner G, Collins E. Fetal effects of regular salicylate ingestion in pregnancy. Lancet 1975;2:338-339.

33. Collins E, Turner G. Maternal effects of regular salicylate ingestion in pregnancy. Lancet 1975;2:335-337.

34. Stuart MJ, Gross SJ, Elrad H, Graber JE. Effects of acetylsalicylic acid ingestion on maternal and neonatal hemostasis. N Engl J Med 1982;307:909-913.

35. Arcilla RA, Thilenius OG, Ranniger K. Congestive heart failure from suspected ductal closure in utero. J Pediatr 1969;75:74-78.

36. Cantor B, Tyler T, Nelson RM. Oligohydramnios and transient neonatal anuria: a possible association with the maternal use of prostaglandin synthetase inhibitors. J Reprod Med 1980;24:220-223.

37. Committee on Drugs, American Academy of Pediatrics. The transfer of drugs and other chemicals into human milk. Pediatrics 1994;93:137-150.

38. Ostensen M. Safety on nonsteroidal anti-inflammatory drugs during pregnancy and lactation. Immunopharmacology 1996;4:31-41.

39. Dawood MY. Nonsteroidal antiinflammatory drugs and reproduction. Am J Obstet Gynecol 1993;169:1255-1265.

40. Ostensen M, Ostensen H. Safety of nonsteroidal antiinflammatory drugs in pregnant patients with rheumatic diseases. J Rheumatol 1996;23:1045-1049.

41. Notarianni LJ, Oldham HG, Bennett PN. Passage of paracetamol into breast milk and its subsequent metabolism by the neonate. Br J Clin Pharmacol 1987;24:63–67.

42. Bitzen PO, Gustafsson B, Jostell KG, Melander A, Wahlin-Boll E. Excretion of paracetamol in human breast milk. Eur J Clin Pharmacol 1981;20:123–125.

43. Berlin CM, SJ Yaffe, M Ragni. Disposition of acetaminophen in milk, saliva, and plasma of lactating women. Pediatr Pharmacol 1980;1:135–141.

44. Findlay JW, DeAngelis RL, Kearney MF, Welch RM, Findlay JM. Analgesic drugs in milk and plasma. Clin Pharmacol Ther 1981;29:625–633.

45. Weibert RT, Townsend RJ, Kaiser, Naynor AJ. Lack of ibuprofen secretion into human milk. Clin Pharm 1982;1:457–458.

46. Walter K, Dilger C. Ibuprofen in human milk. Br J Clin Pharmacol 1997;44:211–212.

47. Lebedes TH, Wojnar-Horton RE, Yapp P, Roberts MJ, Dusci LJ, Hackett LP, Ilett KF. Excretion of indomethacin in breast milk. Br J Clin Pharmacol 1991;32:751–754.

48. Jamali F, Stevens DR. Naproxen excretion in milk and its uptake by the infant. Drug Intell Clin Pharm 1983;17:910–911.

49. Brogden RN, Pinder RM, Sawyer PR, Speight TM, Avery GS. Naproxen: a review of its pharmacological properties and therapeutic efficacy and use. Drugs 1975;9:326–363.

50. Ostensen M. Piroxicam in human breast milk. Eur J Clin Pharmacol 1983;25:829–830.

51. Rathmell JP. Management of non-obstetric pain during pregnancy and lactation. Anesth Analg 1997;85:1077-1087.

52. Meny RG, Naumburg EG, Alger LS, Brill-Miller JL, Brown S. Codeine and the breastfed neonate. J Hum Lact 1993;9:237–240.

53. Kunka RL, Venkataramanan R, Stern RM, Ladik CF. Excretion of propoxyphene and norpropoxyphene in breast milk. Clin Pharmacol Ther 1984;35:675–680.

54. Kunka RL, Yong CL, Ladik CF, Bates TR. Liquid chromatographic determination of propoxyphene and norpropoxyphene in plasma and breast milk. J Pharmacol Sci 1985;74:103–104.

55. Leuschen MP, Wolf LJ, Rayburn WF. Fentanyl excretion in breast milk. Clin Pharmacol 1990;9:336–337.

56. Wittels B, Glosten B, Faure EA, et al. Postcesarean analgesia with both epidural morphine and intravenous patient-controlled analgesia: neurobehavioral outcomes among nursing neonates. Anesth Analg 1997;85:600–606.

57. Wittels B, Scott DT, Sinatra RS. Exogenous opioids in human breast milk and acute neonatal neurobehavior: a preliminary study. Anesthesiology 1990;73:864-869.

58. Zeisler JA, Gardner TD, DeMesquita SA. Lidocaine excretion in breast milk. Drug Intell Clin Pharmacol 1986;20:691-693.

59. Eriksson LS, Gentele C, Oloffson H. PCEA compared to continuous epidural infusion in an ultra-low-dose regimen for labor pain relief: a randomized study. Acta Anaesthesiol Scand 2003;47:1085-1090.

60. Halpern SH, Muir H, Breen TW, Campbell DC, Barrett J, Liston L, Blanchard JW. A multicenter randomized controlled trial comparing patient-controlled epidural with intravenous analgesia for pain relief in labor. Anesth Analg 2004;99:1532–1538.

61. Leighton BL, Halpern SH. The effects of epidural analgesia on labour, maternal, and neonatal outcomes: a systematic review. Am J Obstet Gynecol 2002;186:S69-S77.

62. Baumgarder DJ, Muehl P, Fischer M, Pribbenow B. Effect of labor epidural anesthesia on breast-feeding of healthy full-term newborns delivered vaginally. J Am Board Fam Pract 2003;16:7-13.

63. Bricker L, Lavender T. Parenteral opioids for labor pain relief: A systematic review. J Am Obstet Gynecol 2002;186:S94-S109.

64. Dahl JB, Jeppesen IS, Jorgensen H, Wetterslev J, Moiniche S. Intraoperative and postoperative analgesic efficacy and adverse effects of intrathecal opioids in patients undergoing cesarean section with spinal anesthesia: A qualitative and quantitative systematic review of randomized controlled trials. Anesthesiology 1999;91:1919–27.

65. Hepner DL, Harnett M, Segal S, et al. Herbal medicine use in parturients. Anesth Analg 2002;94:690-693.

66. Eisenberg DM, Kessler RC, Foster C. Unconventional medicine in the United States. Prevalence, costs, and patterns of use. N Engl J Med 1993;328:246-252.

67. Gentz B. Alternative therapies for the management of pain in labor and delivery. Clin Obst Gynecol 2001;44:704-732.

68. Niggeman B, Gruber C. Side-effects of complementary alternative medicine. Allergy 2003;58:707-716.

69. Covarrubias-Gómez A, Nuche-Cabrera E, Téllez-Isaías M. ¿Qué se auto-administra su paciente?: Interacciones farmacológicas de la medicina herbal. Rev Mex Anest 2005;28:32-42.