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Anales de Otorrinolaringología Mexicana

2021, Number 3

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Otorrinolaringología 2021; 66 (3)

Mumps in Otorhinolaryngology: Diagnostic tools for a neverending story with outbreaks and resurgences

García-Callejo FJ, Balaguer-García R, Juantegui-Azpilicueta M

Language: Spanish
References: 22
Page: 182-191
PDF size: 220.82 Kb.


ABSTRACT

Background: Mumps has modified its clinic and epidemiologic characteristics in last decades, and because of this the diagnostic strategy changed too.
Objective: To update the peculiarities of mumps with a strong rooting with Otorhinolaryngology.
Patients and Methods: A retrospective study was carried out in Otolaryngolgy Service of General Hospital of Requena, Valencia, Spain, from January 2017 to June 2020 on patients assisted under mumps suspicion, as well as their direct contacts. Symptomatology and laboratory were registered (blood amylase, serology by enzimoimmunoassay and real time-PCR for virus detection in saliva).
Results: We diagnosed 47 cases in 42 months, with a mean age of 26.29 ± 6.13 years old and a decreased incidence from 19.6/105 inhabitants in 2017 to 6 in 2020. Parotid swelling (mostly unilateral) and fever were the most regular clinic findings (33/47 cases). Thirteen of them were non-symptomatic and detected by mean of tracing infected patients. Diagnostic sensitivity was 54.8% for a first physical exploration but increased to 70.5.% if associated to higher levels of blood amylase, 36% for serology tests and 100% for PCR.
Conclusions: The disease shows cyclic outbreaks affecting young adults above all, with parotid damage mainly unilateral. Antibodies detection only must be employed for seroprevalence studies. Physical exam with blood amylase measurement showed more usefulness, and real time-PCR results in saliva samples were excellent for the diagnosis.


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