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2020, Number 2

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Revista Cubana de Cirugía 2020; 59 (2)

Outcomes of surgical treatment in patients with advanced colorectal cancer

Fernández SLT, Hernández ÁFE, González VJA, Lima PM, González MM

Language: Spanish
References: 30
Page: 1-18
PDF size: 462.80 Kb.


ABSTRACT

Introduction: advanced cancer is cancer that has grown outside the organ in which it originated. Surgical resection is the most effective method to achieve colorectal cancer cure in 50 % of cases.
Objectives: the objective was to evaluate the results of the multidisciplinary treatment, carried out on patients diagnosed with advanced colorectal cancer.
Method: it is an observational, descriptive, ambispective and cross-sectional study at the “Hermanos Ameijeiras” Surgical Clinical Hospital between January 2013 and December 2018. The sample was 219 cases.
Results: 34.2 % of the patients were between 70 and 79 years old. 56.2 % were women. There was a predominance of localization in the ascending colon (37.4 %), in 57.1 % it was moderately differentiated and in 34.2 % in stage IIIA. 7.8 % of the patients had a metastatic relapse, 70.5 % of them in the liver. In 72.6 %, the access route was laparoscopic. Right hemicolectomy was performed in 50.7 %. Complications were observed in 25 patients (35.2 %). 91.3 % of the cases received adjuvant therapy. In 27.4 % there was recurrence. Good results were obtained in the analysis of disease-free time and survival.
Conclusion: we conclude that combined, sequential, and multidisciplinary treatment in advanced colorectal malignancy has demonstrated clinical benefits and increased survival. With an acceptable morbidity and mortality related to the surgical procedure regardless of the access route used. Multivisceral and/or en bloc resections and maximum resection manage to increase the free interval of disease progression and alleviate symptoms.


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