Chao PC, Martínez FJA, Rojas GÁ, Pérez GSJ, Roselló AY

Language: Spanish
References: 28
Page: 1-7
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ABSTRACT

Introduction: The heart failure is a devastating illness for its high mortality. The association between obesity and mortality in this illness is polemic. Objective: To evaluate the influence of the obesity in the mortality of the patients of the masculine sex with heart failure chronicle. Method: we were carried out a prospective study in 109 patients of the masculine sex assisted in the Hospital Ameijeiras for a ten year-old period. Were considered the probability of being free of death, by means of the employment of the method of Kaplan Meier. To identify the association among the clinical variables and of presage in relation to the mortality the relative risk (RR) was determined, to evaluate the value presage the pattern of regression of Cox it was used, Odd Ration (OR) was determined. Results: The probability of surviving the year of pursuit for the obese ones went 0,86 and to the ten years 0,5; those of normal weight 0,69 a year and none to ten years. The presence of ejection fraction of the left ventricle to <40% was related significantly in the analysis univariado with the risk of death, p = 0,05; RR: 7,14 (IC-95%: 1,18-43,1). The proportional risk of mortality in the time for the obese ones presented an OR: 0,835. Conclusions: The presence of obesity in the patients of the masculine sex with heart failure chronicle the mortality didn't increase.

REFERENCES

1. Sun LY, Tu JV, Coutinho T, Turek M, Rubens FD. Mortalidad por insuficiencia cardíaca más alta en mujeres que en hombres. CMAJ. 2018. Disponible en: http: //www.cmaj .ca / lookup / doi / 10.1503 / cmaj.180177

2. Mascote JE, Salcedo DM, Mascote MR. Prevalencia de factores de riesgo para insuficiencia cardíaca y discusión de sus posibles interacciones fisiopatológicas. Rev Med Vozandes 2018; 29: 55 – 65

3. Dirección de registros médicos y estadísticas de salud. Anuario Estadístico de Salud 2018 [Internet]. La Habana: MINSAP; 2018 [citado 6 may 2019]. 91-5 p. Disponible en: http://files.sld.cu/dne/files/2018/04/Anuario-Electronico-Espa%C3%B1ol-2017-ed-2018.pdf

4. Block JP, Subramanian SV, Christakis NA, O’Malley AJ. Population trends and variation in body mass index from 1971 to 2008 in the Framingham heart study offspring cohort. Plos One. 2013;8(5):e63217. Disponible en: https://pubmed.ncbi.nlm.nih.gov/23675464

5. Ho KK, Pinsky JL, Kannel WB, Lavy D . The epidemiology of heart failure: the framingham study. J Am Coll Cardiol. 1993;22:6a-13.

6. Hong S, Lee JH, Kim KM, LeeJ-W, YounY-J, Ahn MS, et.al. There a Sex-Related Difference in the Obesity Paradox in Systolic Heart Failure? Sex-Related Difference in the Obesity Paradox. Yonsei Med J, 2018;59(1):57-62

7. Chahal H, Bluemke DA, Wu CO, McClelland R, Liu K, Steven J Shea SJ, et.al. Heart failure risk prediction in the multi-ethnic study of atherosclerosis. Heart . 2015;101:58–64. PubMed:PMID: 25381326.

8. Horwich TB, Fonarow GC, Hamilton MA, MacLellan WR, Woo MA, Tillisch JA. The relationship between obesity and mortality in patients with heart failure. J Am Coll Cardiol. 2001;38:789-95. PubMed:PMID:11527635.

9. Sharma A, Lavie CJ, Borer JS, Vallakati A, Goel S, Lopez Jimenez F, et al, Meta-analysis of the relation of body mass index to all-cause and cardiovascular mortality and hospitalization in patients with chronic heart failure. Am J Cardiol. 2015;115:1428-34. PubMed:PMID: 25772740.

10. Littnerova S, Parenica J, Spinar J, Vitovec J, Linhart A, Widimsky P, et al. Positive influence of being overweight/obese on long term survival in patients hospitalised due to acute heart failure. PLoS One. 2015;10:e0117-42. PubMed PMID: 25710625.

11. Khalid U, Ather S, Bavishi C, Chan W, Loehr LR, Wruck LM, et al. Pre-morbid body mass index and mortality after incident heart failure: the ARIC Study. J Am Coll Cardiol. 2014;64:2743-9. PubMed PMID: 25541126.

12. ChengYL, Sung SH, Cheng HM, Hsu F, ChaoY G, Chung WY, et.al. Prognostic nutritional index and the risk of mortality in patients with acute heart failure. J Am Heart Assoc. 2017; 6(6):e004876. PubMed: PMID: 28649089. Disponible: https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5669149/

13. Alfonzo Guerra JP. Retos de la paradoja mayores riesgos y más expectativa de vida vs. realidad en la salud. Rev Cubana Med. [Internet]. 2016 [citado 2 Feb 2018];55:59-66.

14. Zhang, J, Begley A, Jackson R, Harrison M, Pellicori P, Clark AL, et.al. Body mass index and all-cause mortality in heart failure patients with normal and reduced ventricular ejection fraction: a dose–response meta-analysis. Clinical Research in Cardiology. 2019; 108:119–132.

15. Clark AL, Chyu J, Horwich TB (2012) The obesity paradox in men versus women with systolic heart failure. Am J Cardiol 110(1):77–82

16. Chao PC. Obesidad y mortalidad en los pacientes con insuficiencia cardiaca crónica. Rev Cubana Med. 2018;57(4). Disponible en: http://scielo.sld.cu/scielo.php?script

17. VogelI P, SteinII A, Marcadenti A. Visceral adiposity index and prognosis among patients with ischemic heart failure. Sao Paulo Med. J. 2016;134(3) 211-218. PubMed.PMID:27191246.

18. Chao Pereira C, Rojas Gutiérrez A, Roselló Azcanio Y, Valdes Espino Y. Comportamiento del índice de masa corporal en relación a la mortalidad de pacientes con insuficiencia cardiaca.. Rev Cubana Med [Internet]. 2015 [citado 22 Ago 2015];51(2). Dsiponible en: http://bvs.sld.cu/revistas/med/vol54_3_15/medsum315.htm

19. Chao Pereira C, Rojas Gutiérrez A, Roselló Azcanio Y, Andre Tiago. Influencia del índice de masa corporal en la mortalidad de pacientes con insuficiencia cardiaca . Rev Cubana Med [Internet]. 2017[citado 22 Abr 2017]56(3). Disponibe en: http://scielo.sld.cu/scielo.php

20. Qin W, Liu F, Wan C. A U-shaped association of body mass index and all-cause mortality in heart failure patients: a dose-response meta-analysis of prospective cohort studies. Cardiovasc Ther. 2017;35:e12232. Disponible en: https://doi.org/10.1111/1755-5922.12232

21. Matsushita M, Shirakabe A, Hata N, Shinada T, Kobayashi N, Tomita K, et.al.. Association between the body mass index and the clinical findings in patients with acute heart failure: evaluation of the obesity paradox in patients with severely decompensated acute Herat failure. Heart Vessels. 2017; 32:600–608: doi 10.1007/s00380-016-0908-9

22. Koen W. Streng, Adriaan A. Voors1, Hans L. Hillege, Stefan D. Ander, John G. Cleland, Kenneth Dickstein, et.al. Waist-to-hip ratio and mortality in herat failure. European Journal of Heart Failure, 2018; 20: 1269–1277: doi:10.1002/ejhf.1244

23. Gribsholt SB, Pedersen L, Richelsen B, Dekkers O, Thomsen RW. Body Mass Index of 92,027 patients acutely admitted to general hospitals in Denmark: Associated clinical characteristics and 30-day mortality. PLoS ONE. 2018; 13(4): e0195853. Disponible en: https://doi.org/10.1371/journal.pone.0195853

24. Chandramouli C, Tay WT, Bamadhaj NS,Tromp J, Teng T-HK, Yap JJL, et al. Association of obesity with heart failure outcomes in 11 Asian regions: A cohort study. PLoS Med. 2016; 16 (9). Disponible en: https://doi.org/10.1371/journal.pmed.1002916

25. Hong S, Hyun JL, Min KK, Lee JW, Youn YJ, Soo MA, et.al. Is There a Sex-Related Difference in the Obesity Paradox in Systolic Heart Failure? Sex-Related Difference in the Obesity Paradox. Yonsei Med J 2018;59(1):57-62

26. Huffman MD, Berry JD, Ning H, Dyer AR, Garside DB, Xuan Cai, et.al . Lifetime risk for heart failure among white and black Americans: cardiovascular lifetime risk pooling project. Am Coll Cardiol. [Internet]. 2013 [cited 2015 May 20];61:1510-7. PubMed:PMID: 23500287.

27. Padwal, R., McAlister, F., McMurray, J. et al. The obesity paradox in heart failure patients with preserved versus reduced ejection fraction: a meta-analysis of individual patient data. Int J Obes. 2014; 38, 1110–1114: doi.org/10.1038/ijo.2013.203

28. Charnigo R, Guglin M. Obesity paradox in heart failure: statistical artifact, or impetus to rethink clinical practice?. Heart Fail Rev. 2017; 22:13–23: doi10.1007/s10741-016-9577-0