2002, Number 1
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Bol Col Mex Urol 2002; 17 (1)
Effects of hyaluronic acid on scaring mechanism in urethral anastomosis. Experimental study
Adán PA, Hernández AG, Landa JS
Language: Spanish
References: 22
Page: 26-31
PDF size: 228.30 Kb.
ABSTRACT
Introduction: The most serious complication in urethral lesions is the obstruction for fibrosis. The objective of this communication is to demonstrate that hyaluronic acid improves the scaring urethra.
Material and methods: To 16 dogs were performed trauma and section of the urethra experimentally. Reconstruction of this lesion by means of oblique anastomosis were performed and to eight animals they are instilled, also, hyaluronic acid.
Results: The best results evaluated clinic, radiological and histopatology was in those animals in whom were placed rod transurethral and hyaluronic acid after having repaired the urethra.
Discussion: Analysis of results demonstrate that the rod transurethral, allows to align the segments maintaining them fixed and the hyaluronic acid diminishes the inflammation degree and fibrosis.
Conclusion: The hyaluronic acid prevents the inflammatory process that contributes to the appearance of the stenosis.
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