2012, Número 03-04
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Medicina & Laboratorio 2012; 18 (03-04)
Enfermedad renal crónica determinada mediante la creatinina sérica
Campuzano MG, Arbeláez GM, Villegas GI, Palacio PD
Idioma: Español
Referencias bibliográficas: 165
Paginas: 109-136
Archivo PDF: 675.89 Kb.
RESUMEN
La enfermedad renal crónica se relaciona con un mayor riesgo de enfermedad renal
crónica terminal, de enfermedades cardiovasculares y de muerte, por lo que se requiere su
diagnóstico desde las primeras etapas de la enfermedad. Para ello, se disponen de un gran
número de ecuaciones para estimar la tasa de filtración glomerular basadas en la concentración
de creatinina sérica. Si bien la creatinina no es el analito ideal para estimar la filtración glomerular,
ésta continuará empleándose hasta que haya una amplia disponibilidad en el medio de otros
marcadores, como la cistatina C, por lo que el laboratorio clínico debe velar por la calidad analítica
de los resultados y por lo tanto, debe determinar la creatinina a través de un método estandarizado
frente a los procedimientos de medida de referencia. El objetivo de este módulo es revisar la
detección de la enfermedad renal crónica desde sus etapas iniciales, a partir de la creatinina
sérica y de la estimación de la tasa de filtración glomerular.
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