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ISSN 2007-4360 (Impreso)
Asociación Mexicana de Periodontología, Colegio de Periodoncistas A.C

2019, Número 3

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Rev Mex Periodontol 2019; 10 (3)


Defensinas humanas y su función en cavidad oral

Ortiz-Casillas MI, Alvizo-Rodríguez CR, Ortíz-García YM, Fuentes-Lerma MG, Gutiérrez-Angulo M, Mariaud-Schmidt RP

Idioma: Español
Referencias bibliográficas: 65
Paginas: 77-83
Archivo PDF: 636.95 Kb.


RESUMEN

La cavidad oral proporciona un entorno cálido y húmedo que hace a la flora bucal normal extremadamente compleja y propicia para la colonización por hongos, virus y bacterias, requiriendo múltiples tipos de defensas para prevenir infecciones. Los péptidos antimicrobianos son importantes contribuyentes para mantener el equilibrio entre la salud y la enfermedad, éstos realizan varias funciones esenciales para la defensa contra los microorganismos, lo que modifica la respuesta inflamatoria local y activa mecanismos de reacción inmunitaria adaptativa, participando de esta manera en la modulación de la respuesta inmunológica, que otorga especificidad funcional y los clasifica en diferentes familias, una de ellas las defensinas. En el presente reporte se hace una revisión de la función y expresión de las defensinas y su relación con la cavidad oral.


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