Villanueva-Castro E, Taylor-Martínez MA, Muñoz-Romero I, De Leo-Vargas R

Idioma: Español
Referencias bibliográficas: 50
Paginas: 202-208
Archivo PDF: 192.90 Kb.

RESUMEN

Los paragangliomas son tumores neuroendocrinos raros del sistema nervioso autónomo que derivan del grupo de células neuroepiteliales llamadas paraganglios. Son tumores intradurales-extramedulares y el sitio de localización espinal más frecuente es la cauda equina. El diagnóstico por estudio de imagen resulta difícil, los paragangliomas son similares a los ependimomas e histopatológicamente similares a los tumores neuroendocrinos. El estudio histopatológico nos da el diagnóstico definitivo, la inmunohistoquímica nos ayuda para el diagnóstico diferencial. La mayoría de ellos son tumores no secretores. El dolor de espalda es el síntoma más común y no se relaciona con taquicardia, enrojecimiento ni hipertensión. El tratamiento de elección es la resección quirúrgica total y no es necesario un tratamiento adicional cuando es exitosa. La mayoría de ellos son benignos, pero puede haber recurrencia en resección incompleta del tumor. La metástasis se presenta en muy pocos casos y el sitio más frecuente es óseo. La radioterapia puede ser necesaria en casos de remoción incompleta o recurrencia.

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