2017, Número 4
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Acta Ortop Mex 2017; 31 (4)
Colágena tipo I y polivinilpirrolidona en combinación con autoinjerto para artrodesis lumbar. Estudio experimental en conejos de Nueva Zelanda
Reyes-Sánchez A, Reyes-Tarrago F, García-Ramos C, Zárate-Kalfópulos B, Estrada-Villaseñor E, Alpizar-Aguirre A
Idioma: Ingles.
Referencias bibliográficas: 44
Paginas: 165-170
Archivo PDF: 169.71 Kb.
RESUMEN
Introducción: Existen diversas estrategias para aumentar la tasa de consolidación de la artrodesis de columna en presencia de injerto óseo autólogo, sin aún comprobar si la adhesión de Colágena tipo I y polivinilpirrolidona (Fibroquel
MR) tienen aplicaciones en este campo.
Objetivo: Determinar la efectividad de la colágena tipo I con polivinilpirrolidona como potenciador óseo en artrodesis posterolateral de conejos.
Métodos: Artrodesis posterolateral en 15 conejos de Nueva Zelanda L5-L6 colocando injerto autólogo del lado izquierdo (Control) e injerto autólogo + 1 ml Fibroquel
MR (Estudio) en el lado derecho de la artrodesis. Eutanasia con resección en bloque del segmento lumbar a las ocho semanas del postoperatorio. Análisis radiográfico, palpación manual y por microscopia de luz de los segmentos fusionados.
Resultados: Se observó consolidación radiográfica en 80% en grupo control y 93% en el estudio, continuidad ósea con patrón trabecular intercalado y hueso de características normales en 12 del lado izquierdo y 14 en el lado derecho.
Conclusiones: La utilización de Colágena tipo I y polivinilpirrolidona puede tener efectos positivos en el proceso de consolidación ósea por lo que se puede recomendar su utilización como reforzador óseo.
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