Gómez SJ, Talamás RP, Aguirre GM

Idioma: Español
Referencias bibliográficas: 20
Paginas: 4-12
Archivo PDF: 862.93 Kb.

RESUMEN

Las proteínas fosfatasas son enzimas que desfosforilan proteínas en residuos de tirosina y serina/treonina y están implicadas en diversos procesos celulares, cuyas funciones han sido mejor caracterizadas en células eucariontes. Sin embargo, en las últimas dos décadas se han identificado y caracterizado estas enzimas en microorganismos infecciosos como los parásitos. Se ha observado que algunas proteínas fosfatasas de parásitos pueden presentar funciones similares a las de algunas células eucariontes, mientras que otras fosfatasas presentan características estructurales y/o funcionales únicas, lo que las hace candidatas para el desarrollo de drogas o como marcadores de diagnóstico. En este escrito se engloba el conocimiento generado a la fecha, acerca de la función de estas enzimas en parásitos de importancia médica y veterinaria.

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