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Instituto Nacional de Neurología y Neurocirugía

2016, Número 1

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Arch Neurocien 2016; 21 (1)


Fisiopatología de la hidrocefalia idiopática de presión normal (parte 1): hidrodinamia venosa y compliancia

Solís SO, López PJL, Ayala GM

Idioma: Español
Referencias bibliográficas: 60
Paginas: 45-54
Archivo PDF: 450.29 Kb.


RESUMEN

Esta revisión esta hecha en dos partes, la parte 1 describirá una de las teorías involucradas en la fisiopatología de la Hidrocefalia Idiopática de Presión Normal cuya importancia hace pensar como una de las principales, que es la afectación y alteración del sistema Hidrodinámico cuyos componentes alteran los mecanismos de homeostasis que tiene como control, siendo estos la ley de Monroe-Kelly y el fenómeno de Windkessel. Al desestabilizar estos mecanismos de homeostasis uno de los parámetros mas afectados será el mecanismo de compliancia, esta se encarga en regular las fuerzas de sístole/diástole para que no existan fluctuaciones entre estas y así brindando una perfusión cerebral adecuada que no fluctué. Una vez alterado el mecanismo de compliancia, aparecerán altera- ciones en el sistema hidrodinámico como el aumento en la presión venosa del seno sagital superior (SSS), repercutiendo a su vez en el drenaje del líquido cefalorraquídeo (LCR), por lo que la compliancia, no solo nos brinda un sistema de amortiguación y distribución de fuerzas para que exista un flujo sanguíneo laminar adecuado, sino que participa en el control adecuado de la entrada y salida de sangre al encéfalo, en la absorción adecuada de LCR y en la perfusión del flujo sanguíneo cerebral. Las limitaciones de nuestra revisión están dadas por la metodología de nuestra búsqueda bibliográfica la cual fue realizada principalmente en PubMed bajo los siguientes términos Mesh: normal pressure hydrocephalus, hydrodinamics, compliance, phisiopathology, windkessel.


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