Carrillo-Esper R, Flores-Rivera OI, Díaz-Ponce Medrano JA, Peña-Pérez CA, Romero-González JP, Cruz-Santana J, Arrendo-Ruiz P, Díaz-Mendoza A, Otero-Méndez N, Palacios-Castañeda A

Idioma: Español
Referencias bibliográficas: 36
Paginas: 580-588
Archivo PDF: 700.43 Kb.

RESUMEN

El traumatismo craneoencefálico grave puede condicionar alteraciones de la conciencia, como un estado de mínima conciencia o un estado vegetativo persistente. Las estrategias farmacológicas están dirigidas a mejorar la recuperación neurológica de estos pacientes. Las vías dopaminérgicas tienen un papel fundamental en el despertar de estos pacientes. Comunicamos el caso de un paciente con estado de mínima conciencia, secundario a traumatismo craneoencefálico grave, que respondió de manera favorable al tratamiento con medicamentos prodopaminérgicos: amantadina más zolpidem. A pesar de la evidencia científica disponible, se necesita más investigación para aclarar el papel del tratamiento farmacológico con amantadina más zolpidem en estados vegetativos y mínimamente conscientes; aunque en la actualidad esta combinación tiene buen posicionamiento como estrategia farmacológica.

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