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2016, Número 1

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Rev Esp Med Quir 2016; 21 (1)


Estrategias de regeneración de la córnea con células troncales epiteliales limbales

Téllez-González MA, Gutiérrez-Salinas J, Suárez-Cuenca JA, Mondragón- Terán P

Idioma: Español
Referencias bibliográficas: 40
Paginas: 24-30
Archivo PDF: 503.12 Kb.


RESUMEN

Las células troncales epiteliales limbales son células unipotentes que se localizan en el limbo esclerocorneal. En las últimas décadas se ha demostrado que estas células tienen un papel importante en el mantenimiento y renovación de la córnea. Su ausencia en este tejido llega a generar complicaciones como la pérdida de transparencia, insuficiencia regenerativa e incluso distintos síndromes. Su derivación y cultivo in vitro es una estrategia potencial en Medicina regenerativa; una vez establecidas las condiciones experimentales óptimas para generar su cultivo en 3D se puede realizar experimentación traslacional en forma de pruebas clínicas, mismas que podrán proveer soluciones a distintos problemas visuales.


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