2015, Número 2
<< Anterior Siguiente >>
Rev Mex Anest 2015; 38 (2)
Ventilación de protección en el transoperatorio
Carrillo-Esper R, de los Monteros-Estrada IE, Montero-Arias MD, Rosales-Gutiérrez AO
Idioma: Español
Referencias bibliográficas: 23
Paginas: 91-97
Archivo PDF: 214.70 Kb.
RESUMEN
La anestesia general condiciona reducción de los volúmenes pulmonares y el desarrollo de atelectasias, lo que induce deterioro del intercambio gaseoso y de la mecánica respiratoria. Los volúmenes corrientes altos sobredistienden las unidades alveolares, lo que favorece el desarrollo de la inflamación. Varios estudios han mostrado que una estrategia ventilatoria protectora durante el transoperatorio a base de bajos volúmenes corrientes, presión positiva al final de la espiración y maniobras de reclutamiento alveolar mejora la función respiratoria y reducen las complicaciones en el postoperatorio.
REFERENCIAS (EN ESTE ARTÍCULO)
Weiser TG, Regenbogen SE, Thompson KD, Haynes AB, Lipsitz SR, Berry WR, et al. An estimation of the global volume of surgery: a modeling strategy based on available data. Lancet. 2008;372:139-144.
Hedenstierna G, Edmark L. The effects of anesthesia and muscle paralysis on the respiratory system. Intensive Care Med. 2005;31:1327-1335.
Strandberg A, Tokics L, Brismar B, Lundquist H, Hedenstierna G. Constitutional factors promoting development of atelectasis during anaesthesia. Acta Anaesthesiol Scand. 1987;31:21-24.
Farber N, Pagel P, Warltier D. Pulmonary pharmacology en Miller’s anesthesia. 7th ed. USA: Churchill Livingstone; 2010.
Amato M, Barbas C, Medeiros D, Magaldi R, Schettino G, Filho G, et al. Effect of a protective-ventilation strategy on mortality in the acute respiratory distress syndrome. N Engl J Med. 1998;338:347-354.
Katzenstein A, Askin F. Acute lung injury patterns: diffuse alveolar damage and bronchiolitis obliterans-organizing pneumonia. In: Katzenstein A, editor. Surgical pathology of non-neoplastic lung disease. 3rd ed. Philadelphia: WB Saunders; 1977. pp. 17-46.
Marini JJ, Gattinoni L. Ventilatory management of acute respiratory distress syndrome: a consensus of two. Crit Care Med. 2004;32:250-255.
Ochs M, Nyengaard JR, Jung A, Knudsen L, Voigt M, Wahlers T, et al. The number of alveoli in the human lung. Am J Respir Crit Care Med. 2004;169:120-124.
Fernández-Pérez ER, Keegan MT, Brown DR. Intraoperative tidal volume as a risk factor for respiratory failure after pneumonectomy. Anesthesiology. 2006;105:14-18.
Uhlig S. Ventilation-induced lung injury and mechanotransduction: stretching too far? Am J Physiol Lung Cell Mol Physiol. 2002;282:892-896.
Vlahakis N, Schroeder M, Limper A, Hubmayr R. Stretch induces cytokine release by alveolar epitheial cells in vitro. Am J Physiol. 1999;277:167-173.
Pugin J, Dunn I, Jolliet P, Tassaux D, Magnenat JL, Nicod L, et al. Activation of human macrophages by mechanical ventilation in vitro. Am J Physiol. 1998;275:1040-1050.
Meier T, Lange A, Papenberg H, Ziemann M, Fetrop C, Uhlig U, et al. Pulmonary cytokine responses during mechanical ventilation of noninjured lungs with and without end expiratory pressure. Anesth Analg. 2008;107:1265-1275.
Amato M, Barbas C, Medeiros D, Schettino G, Filho G, Kairalla R, et al. Beneficial effects of the “open lung approach” with low distending pressures in acute respiratory distress syndrome. A prospective randomized study on mechanical ventilation. Am J of Respir and Crit Care Med. 1995;152:1835-1846.
Wrigge H, Zinserling J, Stüber F, von Spiegel T, Hering R, Wetegrove S, et al. Effects of mechanical ventilation on release of cytokines into systemic circulation in patients with normal pulmonary function. Anesthesiology. 2000;93:1413-1417.
Ranieri V, Suter P, Tortorella C, De Tullio R, Dayer J, Brienza A, et al. Effect of mechanical ventilation on inflammatory mediators in patients with acute respiratory distress syndrome a randomized controlled trial. JAMA. 1999;281:54-61.
Ventilation with lower tidal volumes as compared with traditional tidal volumes for acute lung injury and the acute respiratory distress syndrome. The Acute Respiratory Distress Syndrome Network. N Engl J Med. 2000;342:1301-1308.
Brower R, Shanholtz C, Fessler H, Shade D, White P, Wiener C, et al. Prospective, randomized, controlled clinical trial comparing traditional versus reduced tidal volume ventilation in acute respiratory distress syndrome patients. Crit Care Med. 1999; 27:1492-1498.
Futier E, Constantin J, Paugam-Burtz C, Pascal J, Eurin M, Neuschwander A, et al. A trial of intraoperative low-tidal-volume ventilation in abdominal surgery. New England Journal of Medicine. 2013;369:428-437.
Zilberberg M, Shorr A. Ventilator-associated pneumonia: the clinical pulmonary infection score as a surrogate for diagnostics and outcome. Clin Infect Dis. 2010;51:131-135.
Treschan T, Kaisers W, Schaefer M, Bastin B, Schmalz U, Wania V, et al. Ventilation with low tidal volumes during upper abdominal surgery does not improve postoperative lung function. Brit J Anaesth. 2012;109:263-271.
Sundar S, Novack V, Jervis K, Bender S, Lerner A, Panzica P, et al. Influence of low tidal volume ventilation on time to extubation in cardiac surgical patients. Anesthesiology. 2011;114:1102-1110.
Lellouche F, Dionne S, Simard S, Bussieres J, Dagenais F. High tidal volumes in mechanically ventilated patients increase organ dysfunction after cardiac surgery. Anesthesiology. 2012;116:1072-1082.