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Órgano Oficial del Colegio Mexicano de Alergia, Asma e Inmunología Pediátrica y de la Asociación Latinoamericana de Pediatría

2014, Número 3

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Alerg Asma Inmunol Pediatr 2014; 23 (3)


Dermatitis atópica y vitamina D

Guerrero AGL, Huerta LJG

Idioma: Español
Referencias bibliográficas: 48
Paginas: 65-70
Archivo PDF: 128.46 Kb.


RESUMEN

Actualmente se sabe que la dermatitis atópica es una enfermedad en la que la función de barrera se encuentra alterada, dicha alteración está determinada genéticamente. Clínicamente, esto se traduce en una piel intensamente pruriginosa e inflamada que permite la penetración de irritantes y alérgenos y predispone a colonización e infección por determinados microorganismos. El papel de la vitamina D entre los diversos factores etiológicos se ha enfatizado en los últimos años. Se considera que puede estar asociada con el riesgo de padecer dermatitis atópica y con su severidad. Tal asociación es sugerida por los datos epidemiológicos y experimentales recientes. En esta revisión, se analiza la evidencia a favor y en contra de esta polémica relación, haciendo hincapié en los posibles mecanismos etiopatogénicos implicados.


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