2005, Número 3-4
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Microbiología 2005; 47 (3-4)
Proteínas con dominios GGDEF y EAL: su función en el metabolismo bacteriano
Marcela Méndez-Ortiz MM, Membrillo-Hernández J
Idioma: Español
Referencias bibliográficas: 54
Paginas: 130-139
Archivo PDF: 119.82 Kb.
RESUMEN
La disponibilidad de las secuencias de múltiples genomas de bacterias ha permitido estudiar la presencia de dominios proteicos comunes para muchas especies bacterianas. Recientemente se han descrito los dominios GGDEF y EAL los cuales presumiblemente tienen la función de diguanilato ciclasa (c-di-GMP sintasa) y fosfodiesterasa de c-di-GMP respectivamente. El c-di-GMP se ha involucrado en la producción de celulosa bacteriana así como en la modificación de la superficie celular que le permite regular la formación de biopelículas, la motilidad y la virulencia entre otros procesos bacterianos.
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