2013, Número 4
<< Anterior Siguiente >>
Rev Mex Anest 2013; 36 (4)
Anestesia para endoscopía digestiva en el paciente cardiópata isquémico
Gómez-Ríos N, Rodríguez-Ortega MF, Rojas-Sánchez A, Alonso-Mercado JC, Pérez-Bustamante J, Jaymes-Nuñez A, Vargas-Trujillo C
Idioma: Español
Referencias bibliográficas: 124
Paginas: 257-274
Archivo PDF: 275.11 Kb.
RESUMEN
El gran avance que ha tenido la endoscopía digestiva en los últimos años ha hecho que el número de procedimientos aumente, haciendo de éste una práctica común en la medicina moderna; por ello, en el paciente cardiópata se solicita cada vez más la sedación-analgesia para este tipo de intervenciones.
Objetivo: Analizar el tratamiento anestésico en el paciente cardiópata al que se le realizó algún procedimiento endoscópico.
Sede: Centro Médico del Instituto de Seguridad Social del Estado de México y Municipios.
Diseño: Estudio descriptivo, observacional, transversal y prospectivo.
Análisis estadístico: Porcentaje como medida de resumen para variables cualitativas.
Método: Se revisaron los expedientes clínicos de los pacientes a los que se les realizó algún procedimiento endoscópico y presentaban antecedente de cardiopatía isquémica, de junio de 2006 a junio de 2011. Se analizaron las siguientes variables: edad y género, tratamiento y tiempo de evolución de la cardiopatía isquémica, comorbilidades, procedimiento endoscópico (alto, bajo o colangiopancreatografía retrógrada endoscópica), tiempo del procedimiento (diagnóstico o terapéutico), hallazgos electrocardiográficos transprocedimiento, protocolo anestésico empleado y morbimortalidad.
Resultados: 82 pacientes con antecedente de cardiopatía isquémica, promedio de edad de 55 años, género masculino 58.6, con tratamiento médico más trombólisis a 29 pacientes, intervencionismo en 39 y procedimiento quirúrgico en 14, con tiempo promedio de evolución de seis meses, con terapia dual en 66 pacientes, 42 con antecedente de diabetes mellitus tipo 2. Realizando 45 esofagogastroduodenofibroscopías, 25 rectosigmoidocolonofibroscopías y 12 colangiopancreatografías retrógradas endoscópicas, la alteración electrocardiográfica que se presentó con más frecuencia fue extrasístole ventricular en 23 pacientes, no se reportó isquemia o infarto agudo al miocardio, no se reportaron complicaciones inherentes al procedimiento anestésico ni mortalidad cardiovascular a un año de seguimiento.
Conclusión: Es necesaria la estratificación del riesgo quirúrgico y complejidad del procedimiento en la población cardiópata isquémica para la adecuada decisión anestésica y así disminuir las complicaciones perioperatorias.
REFERENCIAS (EN ESTE ARTÍCULO)
Pastor Torres LF, Santiago RR, Honorato PJ, Junquera PC, Navarro SE, Ortigosa AF et al. Guías de práctica de la Sociedad Española de Cardiología en la valoración del riesgo quirúrgico del paciente cardiópata sometido a cirugía no cardiaca. Rev Esp Cardiol. 2001;54:186-193.
Arrowsmith JB, Gerstman BB, Fleischer DE. Results from the American Society for Gastrointestinal Endoscopy/ U.S. Food and drug administration collaborative study on complication rates and drug use during gastrointestinal endoscopy. Gastrointest Endosc. 1991;37:421-427.
Adler DG, Baron TH, Davila RE. Standards of Practice Committee of American Society for Gastrointestinal Endoscopy. ASGE guideline: the role of ERCP in diseases of the biliary tract and pancreas. Gastrointest Endosc. 2005;62:1-8.
Lichtenstein D, Jagannath S, Baron T. Sedation and anesthesia in GI endoscopy. Gastrointest Endosc. 2008;68:815-826.
Vargo J, DeLegge M, Feld A, Gerstenberger P, Kwo P, Lightdale J, et al. Multisociety sedations curriculum for gastrointestinal endoscopy. Gastrointest Endosc. 2012;76:1-25.
Vargo J, Zuccaro G Jr, Dumot J, Shermock K, Morrow J, Conwell D et al. Gastroenterologist-administered propofol versus meperidine and midazolam for advanced upper endoscopy: a prospective, randomized trial. Gastroenterology. 2002;123:8-16.
Norma Oficial Mexicana. Para la práctica de la anestesiología. NOM-006-SSA3-2011. Diario Oficial de la Federación.
Kotobo F, Twersky R. Anesthesia outside the operating room: general overview and monitoring standers. Int Anesthesiol Clin. 2003;41:1-15.
Waring J, Baron T, Hirota W. ASGE standards of practice committee. Guidelines for conscious sedation and monitoring during gastrointestinal endoscopy. Gastrointest Endosc. 2003;58:317-322.
Gross J, Bailey P, Caplan R. American Society of Anesthesiologists task force on sedation and analgesia by non-anesthesiologists. Anesthesiology. 2002;96:1004-1007.
Wells PH, Kaplan JA. Optimal management of patients with ischemic heart disease for noncardiac surgery by complementary anesthesiologist and cardiologist interaction. Am Heart J. 1981;102:1029-1037.
Faigel D, Baron T, Goldstein J, Hirota W, Jacobson B, Johanson J et al. Guidelines for the use of deep sedation and anesthesia for GI endoscopy. Gastrointest Endosc. 2002;56:613-617.
Rex D, Imperiale T, Portish V. Patients willing to try colonoscopy without sedation: associated clinical factors and results of a randomized controlled trial. Gastrointest Endosc. 1999;49:554-559.
Raby KE, Goldman L, Creager MA, Cook EF, Weinberg MC, Whittemore AD et al. Correlation between preoperative ischemia and major cardiac events after peripherals vascular surgery. N Engl J Med. 1989;321:1296-1300.
Bhatt D, Scheiman J, Abraham N. ACCF/ACG/AHA 2008 expert consensus document on reducing the gastrointestinal risks of antiplatelet therapy and NSAID use: a report of the American College of Cardiology Foundation Task Force on Clinical expert consensus documents. J Am Coll Cardiol. 2008;52:1502-1517.
Antman E, Hand M, Armstrong P. 2007 focused update of the ACC/AHA 2004 guidelines for management of patients with ST-elevation myocardical infarction: a report of the American College of Cardiology/American Heart Association Task Force on Practice Guidelines (writing group to review new evidence and update the ACC/AHA 2004 guidelines for management of patients with ST-elevation myocardical infarction). J Am Coll Cardiol. 2008;51:210-247.
Bhatt D, Bertrand M, Berger P. Meta-analysis of randomized and registry comparisons of ticlopidine with clopidogrel after stenting. J Am Coll Cardiol. 2002;39:9-14.
Bertrand M, Rupprecht H, Urban P. Double-blind study of the safety of clopidogrel with and without a loading dose in combination with aspirin compared with ticlopidine in combination with aspirin after coronary stenting: the Clopidogrel Aspirin Stent International Cooperative Study (CLASSICS). Circulation. 2000;102:624-629.
Bhatt D, Fox K, Hacke W. Clopidogrel and aspirin versus aspirin alone for the prevention of atherothrombotic events. N Engl J Med. 2006:354;1706-1717.
Goldman L, Caldera D, Nussbaum S, Southwick F, Krogstad D, Murray B et al. Multifactorial index of cardiac risk in non cardiac surgical procedures. N Engl J Med. 1977;297:845-850.
Goldman L, Caldera D, Southwick F, Nussbaum S, Murray B, O’Malley T et al. Cardiac risk factors and complications in non-cardiac surgery. Medicine. 1978;57:357-370.
Gangi S, Saidia F, Patel K. Cardiovascular complications after GI endoscopy: occurrence and risks in a large hospital system. Gastrointest Endosc. 2004;60:679-685.
Sharma V, Nguyen C, Crowell M. A national study of cardiopulmonary unplanned events after GI endoscopy. Gastrointest Endosc. 2007;66:27-34.
Mallampati S, Gatt S, Gugino L. A clinical sign to predict difficult tracheal intubation: a prospective study. Can Anaesth Soc J. 1985;32:429-434.
Detsky A, Abrams H, McLaughlin J. Predicting cardiac complications in patients undergoing noncardiac surgery. J Gen Intern Med. 1986;1:211-219.
Lee T, Marcantonio E, Mangione C. Derivation and prospective validation of simple index for prediction of cardiac risk of major noncardiac surgery. Circulation. 1999;100:1043-1049.
Mille LJ, Hernández ZS. Manejo anestésico para procedimientos fuera del quirófano. Rev Mex Anest. 2007;30:202-207.
Pérez C. Disminuyendo los riesgos en los procedimientos fuera de quirófano. Cir Gen. 2010;32:103-105.
Opalín GL. Anestesia y sedación fuera de quirófano. Rev Mex Anest. 2004;27:106-107.
Peralta ZE. Controversias en el manejo anestésico para cirugía ambulatoria. Rev Mex Anest. 2004;27:102-105.
Gómez RN, Rodríguez OM, Palma MJ, Hernández MM, Juárez LA. Protocolo anestésico para el tratamiento endovascular percutáneo del aneurisma de aorta abdominal (AAA). Experiencia inicial en el Centro Médico ISSEMyM. Rev Mex Anest. 2010;33:17-22.
Opalín GL. Anestesia en áreas fuera de quirófano. Rev Mex Anest. 2008;31:217-219.
Organización Mundial de la Salud. Lista OMS de verificación de la seguridad de la cirugía. 1ª ed. Francia: Organización Mundial de la Salud; 2008: Disponible en: www.who.int/patientsafety/safesurgery/sssl_manual_spanish.pdf
Ramsay M, Savege T, Simpson B, Goodwin R. Controlled sedation with alphaxalone-alphadolone. BMJ. 1974;2:656-659.
Aldrete S. Aplicación de la escala de recuperación de Aldrete en cirugía ambulatoria. Anest Mex. 2000;12:1-2.
Rao T, Jacobs K, El-Etr A. Reinfarction following anesthesia in patients with myocardial infarction. Anesthesiology. 1983;59:499-505.
Wells PH, Kaplan J. Optimal management of patients with ischemic heart disease for noncardiac surgery by complementary anesthesiologist and cardiologist interaction. Am heart J. 1981;102:1029-1037.
Foster E, Davis K, Carpenter J, Abele S, Fray D. Risk of noncardiac operation in patients with defined coronary disease: The Coronary Artery Surgery Study (CASS) registry experience. Ann Thorac Surg. 1986;41:42-50.
Jeffrey C, Kunsman J, Cullen D, Brewster D. A prospective evaluation of cardiac risk index. Anesthesiology. 1983;58:462-464.
Hernández-de la Vega L. Sedación consciente e inconsciente. Rev Mex Anest. 2004;27:95-97.
Delgado CR, Martínez SR. Opioides en anestesia ambulatoria. Rev Mex Anest. 2010;33:118-121.
Peralta ZE. Actualidades de agentes inhalados en anestesia ambulatoria. Rev Mex Anest. 2010;33:115-117.
Vargo J, Zuccaro G, Dumont J. Gastroenterologist-administered propofol versus meperidine and midazolam for advanced upper endoscopy: a prospective, randomized trial. Gastroneterology. 2002;123:8-16.
Olguín RC, Sobrino CS, López AJ. Correlación entre el grado de ansiedad basal y los requerimientos anestésicos durante la endoscopía. Rev Mex Anest. 2010;33:128-141.
Bravo D, Mosqueira L, Miller C, Cárcamo C. Sedación en la endoscopía digestiva. Cuad Cir. 2008;22:43-49.
Ruiz I. Anestesia, analgesia y sedación en los procedimientos endoscópicos. Rev Colomb Gastroenterol. 2004;19:193-194.
CAPRIE Steering Committee. A randomised, blinded, trial of clopidogrel versus aspirin in patients at risk of ischaemic events (CAPRIE). Lancet. 1996;348:1329-1339.
Kimura T, Morimoto T, Nakagawa Y. Antiplatelet therapy and stent thrombosis after sirolimus-eluting stent implantation. Circulation. 2009;119:987-995.
Eisenberg M, Richard P, Libersan D. Safety of short-term discontinuation of antiplatelet therapy in patients with drug-eluting stents. Circulation. 2009;119:1634-1642.
Gilard M, Arnaud B, Cornily J. Influence of omeprazole on the antiplatelet action of clopidogrel associated with aspirin: the randomized, double-blind OCLA (omeprazole clopidogrel aspirin) study. J Am Coll Cardiol. 2008;51:256-260.
Ho P, Maddox T, Wang L. Risk of adverse outcomes associated with concomitant use of clopidogrel and proton pump inhibitors following acute coronary syndrome. JAMA. 2009;301:937-44.
Sung J, Ching J. Can aspirin be reintroduced with PPI inhibitor infusion after endoscopic hemostasis: a double-blind randomized controlled trial. Gastroenterology. 2008;130:44.
Quine MA, Bell GD, McCloy RF, Charlton JE, Devlin HB, Hopkins A. Prospective audit. Of upper gastrointestinal endoscopy in two regions of England: safety, staffing and sedation methods. Gut. 1995;36:462-467.
Rogers BH, Silvis SE, Nebel OT. Complications of flexible fiberoptic colonoscopy and polypectomy. Gastrointest Endosc. 1975;22:73-77.
Alam M, Schuman B, Duvernoy W. Continuo’s electrocardiographic monitoring during colonoscopy. Gastrointest Endosc. 1976;22:203-205.
Fletcher G, Earnest D, Shuford W. Electrocardiographic changes during routine sigmoidoscopy. Arch Intern Med. 1968;122:483-486.
Bell G, Bown S, Morden A. Prevention of hypoxemia during upper gastrointestinal endoscopy by means of oxygen via nasal cannula. Lancet. 1987;1:1022-1024.
Bower A, Ripepi A, Dilger J. Bispectral index monitoring of sedation during endoscopy. Gastrointest Endosc. 2000;52:192-196.
Cohen L, Delegge M, Aisenberg J. AGA institute review of endoscopic sedation. Gastroenterology. 2007;133:675-701.
Laluna L, Allen M, Di Marino A. The comparison of midazolam and topical lidocaine spray versus the combination of midazolam, meperidine, and topical lidocaine spray to sedate patients for upper endoscopy. Gastrointest Endosc. 2001;53:289-293.
Soma Y, Saito H, Kishibe T, Takahashi T, Tanaka H, Munakata A. Evaluation of topical pharyngeal anesthesia for upper endoscopy including factors associated with patient tolerance. Gastrointest Endosc. 2001;53:14-18.
Griffin S, Chung S, Leung J. Effect of intranasal oxygen on hypoxia and tachycardia during endoscopic cholangiopancreatography. BMJ. 1990;300:83-84.
Jurell K, O’Connor K, Slack J. Effect of supplemental oxygen on cardiopulmonary changes during gastrointestinal endoscopy. Gastrointest Endosc. 1994;40:665-670.
Pedersen T, Moller A, Pedersen B. Pulse oximetry for perioperative monitoring systematic review of randomized, controlled trials. Anesth Analg. 2003;96:426-431.
Zafar S, Ayappa I, Norman R. Choice of oximeter affects apnea-hypopnea-index. Chest. 2005;127:80-88.
Takahashi Y, Tanaka H, Kinjo M, Sakumoto K. Sedation-free colonoscopy. Dis Colon Rectum. 2005;48:855-859.
Takahashi Y, Tanaka H, Kinjo M, Sakumoto K. Prospective evaluation of factors predicting difficulty and pain during sedation-free colonoscopy. Dis Colon Rectum. 2005;48:1295-300.
Terruzzi V, Meucci G, Radaelli F, Terreni N, Minoli G. Routine versus «on demand» sedation and analgesia for colonoscopy: a prospective randomized controlled trial. Gastrointest Endosc. 2001;54:169-174.
Chang A, Solinger M, Yang D, Chen Y. Impact of flumazenil on recovery after outpatient endoscopy: a placebo-controlled trial. Gastrointest Endosc. 1999;49:573-579.
Mathew P, Ona F, Damevski K. Arrhytmias during upper gastrointestinal endoscopy. Angiology. 1979;30:834-840.
Tezuka K, Nomura M, Saito K. Changes in autonomic nervous activity during colonoscopy using spectral analysis of heart rate variability. Digestive Endoscopy. 2000;12:155-161.
Marsh W, Bronner M, Yantis P. Ventricular ectopy associated with peroral colonic lavage. Gastrointest Endosc. 1986;32:259-263.
Cappell M, Abdullah M. Management of gastrointestinal bleeding induced by gastrointestinal endoscopy. Gastroenterol Clin North Am. 2000;29:125-167.
Veitch A, Baglin T, Gershlick A. Guidelines for the management of anticoagulant and antiplatelet therapy in patients undergoing endoscopic procedures. Gut. 2008;57:1322-1329.
Sung J, Chung S, Low J. Systemic absorption of epinephrine after endoscopic submucosal injection in patients with bleeding peptic ulcers. Gastrointest Endosc. 1993;39:20-22.
Tolliver K, Rex D. Colonoscopic polypectomy. Gastroenterol Clin North Am. 2008;37:229-251.
Rabeneck L, Paszat L, Hilsden R. Bleeding and perforation after outpatient colonoscopy and their risk factors in usual clinical practice. Gastroenterology. 2008;135:1899-1906.
Watabe H, Yamaji Y, Okamoto M. Risk assessment for delayed hemorrhagic complication of colonic polypectomy: polyp-related factors and patient-related factors. Gastrointest Endosc. 2006;64:73-78.
Singaram C, Torbey C, Jacoby R. Delayed postpolypectomy bleeding. Am J Gasteroenterol. 1995;90:146-147.
Nelson D, McQuaid K, Bond J. Procedural success and complications for large-scale screening colonoscopy. Gastrointest Endosc. 2002;55:307-314.
Sorbi D, Norton I, Conio M. Postpolypectomy lower GI bleeding: descriptive analysis. Gastrointest Endosc. 2000;51:690-696.
Sawhney M, Salfiti N, Nelson D. Risk factors for severe delayed postpolypectomy bleeding. Endoscopy. 2008;40:115-119.
Hui A, Wong R, Ching J. Risk of colonoscopic polypectomy bleeding with anticoagulants and antiplatelet agents: analysis of 1,657 cases. Gastrointest Endosc. 2004;59:44-48.
Yousfi M, Gostout C, Baron T. Postpolypectomy lower gastrointestinal bleeding: potential role of aspirin. Am J Gastroenterol. 2004;99:1785-1789.
Di Giorgio P, De Luca L, Calcagno G. Detachable snare versus epinephrine injection in the prevention of postpolypectomy bleeding: a randomized and controlled study. Endoscopy. 2004;36:860-863.
Paspatis G, Paraskeva K, Theodoropoulou A. A prospective, randomized comparison of adrenaline injection in combination with detachable snare versus adrenaline injection alone in the prevention of postpolypectomy bleeding in large colonic polyps. Am J Gastroenterol. 2006;101:2805-2813.
Eckardt V, Kanzler G, Schmitt T, Eckardt A, Bernhard G. Complications and adverse effects of colonoscopy with selective sedation. Gastrointest Endosc. 1999;49:560-565.
Kundu R, Pleskow D. Biliary and pancreatic stents: complications and management. Tech Gastrointest Endosc. 2008;125-134.
Mallery J, Baron T, Dominitz J. Complications of ERCP. Gastrointest Endosc. 2003;57:633-638.
Masci E, Toti G, Mariani A. Complications of diagnostic and therapeutic ERCP: a prospective multicenter study. Am J Gastroenterol. 2001;96:417-423.
Friedland S, Soetikno R. Colonoscopy with polypectomy in anticoagulated patients. Gastrointest Endosc. 2006;64:98-100.
Howell D, Loew B, Sanders M. Use of hemostatic clips in patients undergoing colonoscopy in the setting of coumadin antithrombotic therapy. Gastrointest Endosc. 2006;63:99.
Mehta S, Yusuf S, Peters R. Effects of pretreatment with clopidogrel and aspirin followed by long-term therapy in patients undergoing percutaneous coronary intervention: the PCI-CURE study. Lancet. 2001;358:527-533.
Lloyd-Jones D, Adams R, Carnethon M. Heart disease and stroke statistics-2009 update: a report from the American Heart Association Statistics Committee and Stroke statistics subcommittee. Circulation. 2009;119:480-486.
Lloyd-Jones D, Larson M, Beiser A, Levy D. Lifetime risk of developing coronary heart disease. Lancet. 1999;353:89-92.
Ford E, Ajani U, Croft J. Explaining the decrease in U.S. deaths from coronary disease 1980-2000. N Engl J Med. 2007;356:2388-2398.
Schouten O, van Domburg R, Bax J. Noncardiac surgery after coronary stenting: early surgery and interruption of antiplatelet therapy are associated with increase in major adverse cardiac events. J Am Coll Cardiol. 2007;49:122-124.
Wilson S, Fasseas P, Orford J. Clinical outcome of patients undergoing non-cardiac surgery in the two months following coronary stenting. J Am Coll Cardiol. 2003;42:234-240.
Kaluza G, Joseph J, Lee J. Catastrophic outcomes of noncardiac surgery soon after coronary stenting. J Am Coll Cardiol. 2000;35:1288-1294.
Grines C, Bonow R, Casey D. Prevention of premature discontinuation of dual antiplatelet therapy in patients with coronary artery stents: a science advisory from the American Heart Association, American College of Cardiology, Society for Cardiovascular Angiography and Interventions, American College of Surgeons and American Dental Association, with representation from the American College of Physicians. J Am Coll Cardiol. 2007;49:734-739.
Finn A, Joner M, Nakazawa G. Pathological correlates of late drug-eluting stent thrombosis: strut coverage as a marker of endothelization. Circulation. 2007;115:2435-2341.
Eisenstein E, Anstrom K, Kong D. Clopidogrel use and long-term clinical outcomes after drug-eluting stent implantation. JAMA. 2007;297:159-168.
Airoldi F, Colombo A, Morici N. Incidence and predictors of drug-eluting stent thrombosis during and after discontinuation of thienopyridine treatment. Circulation. 2007;116:745-754.
Patrono C, Coller B, FitzGerald G, Hirsh J, Roth G. Platelet-active drugs: the relationships among dose, effectiveness, and side effects: the Seventh ACCP Conference on Antithrombotic and Thrombolytic Therapy. Chest. 2004;126:s234-264.
Diener H, Bogousslavsky J, Brass L. Aspirin and clopidogrel compared with clopidogrel alone after recent ischemic stroke or transient ischaemic attack in high-risk patients (MATCH) randomized, double-blind, placebo-controlled trial. Lancet. 2004;364:331-337.
Choudari C, Palmer K. Acute gastrointestinal haemorrhage in patients treated with anticoagulant drugs. Gut. 1995;36:483-484.
Sivak M. Trained in ERCP. Gastrointest Endosc. 2003;58:412-414.
Cotton P, Garrow D, Gallagher J. Risk factors for complications after ERCP: a multivariate analysis of 11,497 procedures over 12 years. Gastrointest Endosc. 2009;70:80-88.
Anderson M, Fisher L, Jain R, Evans J, Appalaneni V, Ben-Menachem T et al. Complications of ERCP. Gastrointest Endosc. 2012;75:467-473.
Williams E, Taylor S, Fairclough P. Risk factors for complication following ERCP; results of a large-scale, prospective multicenter study. Endoscopy. 2007;39:793-801.
Wehrmann T, Kokabpick S, Lmbcke B. Efficacy and safety of intravenous propofol sedation during routine ERCP: a prospective, controlled study. Gastrointest Endosc. 1999;49:677-683.
Riphaus A, Stergiou N, Wehrmann T. Sedation with propofol for routine ERCP in high-risk octogenarians: a randomized, controlled study. Am J Gastroenterol. 2005;100:1957-1963.
Kongkam P, Rerknimitr R, Punyathavorm S. Propofol infusion versus intermittent meperidine and midazolam injection for conscious sedation in ERCP. J Gastrointest Liver Dis. 2008;17:291-297.
Cote G, Hovis R, Ansstas MA. Incidence of sedation-related complications with propofol use during advanced endoscopic procedures. Clin Gastroenterol Hepatol. 2010;8:137-142.
Johanson JF, Cooper G, Eisen GM. American Society of Gastrointestinal Endoscopy Outcomes Research Committee. Quality assessment of ERCP: endoscopic retrograde cholangiopancreatography. Gastrointest Endosc. 2002;56:165-169.
Freeman ML, Nelson DB, Sherman S. Complications of endoscopic biliary sphinterotomy. N Engl Med. 1996;335:909-918.
Loperfido S, Angelini G, Benedetti G. Major early complications from diagnostic and therapeutic ERCP: a prospective multicenter study. Gastronintest Endosc. 1998;48:1-10.
Andriulli A, Loperfido S, Napolitano G. Incidence rates of post-ERCP complications: a systematic survey of prospective studies. Am J Gastroenterol. 2007;102:1781-1788.
Fisher L, Fisher A, Thomson A. Cardiopulmonary complications of ERCP in older patients. Gastrointest Endosc. 2006;63:948-955.
Qadeer M, Vargo J, Dumot J. Capnography monitoring of respiratory activity improves safety of sedation for endoscopic cholangiopancretography and ultrasonography. Gastroenterology. 2009;136:1568-1576.
Jung M, Hofmann C, Kiesslich R, Brackertz A. Improved sedation in diagnostic and therapeutic ERCP: propofol is an alternative to midazolam. Endoscopy. 2000;32:233-238.
Riphaus A, Stergiou N, Wehrmann T. Sedation with propofol for routine ERCP in high-risk octogenarians: a randomized, controlled study. Am J Gastroenterol. 2005;100:1957-1963.
Osborn I, Cohen J, Soper R, Roth L. Laryngeal mask airway-a novel method of airway protection during ERCP: comparison with endotracheal intubation. Gastrointest Endosc. 2002;56:122-128.
Hall J, Uhrich T, Barney J, Arain S, Ebert J. Sedative amnestic and analgesic properties of small-dose dexmedetomidina infusion. Anesth Analg. 2000;90:699-705.