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Colegio de Medicina Interna de México.

2013, Número 6

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Med Int Mex 2013; 29 (6)


Inmunosenescencia y fragilidad: una mirada actual

Romero-Cabrera ÁJ, Amores-Hernández L, Fernández- Casteleiro E

Idioma: Español
Referencias bibliográficas: 74
Paginas: 605-611
Archivo PDF: 476.06 Kb.


RESUMEN

La inmunosenescencia se refiere a los cambios que se producen en el sistema inmunitario a causa del envejecimiento y que afectan la inmunidad innata y adaptativa. Estos cambios son más marcados en ancianos frágiles en quienes un estado inflamatorio crónico (envejecimiento inflamatorio, inflammageing) constituye un mecanismo importante a considerar. En este artículo se revisa la naturaleza de estos cambios y se actualizan los vínculos entre inmunosenescencia y fragilidad reflejados en las publicaciones actuales.


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