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2013, Número 3

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Rev Mex Traspl 2013; 2 (3)


¿Cuáles son los efectos neuropsicológicos durante la primera infancia en niños expuestos a inmunosupresores en el desarrollo intrauterino? Inmunosupresores y efectos cognitivos a largo plazo

Lascarez S, Vélez A, Sánchez S, Orozco G, Cruz F

Idioma: Español
Referencias bibliográficas: 44
Paginas: 107-114
Archivo PDF: 221.96 Kb.


RESUMEN

México ocupa el noveno lugar en trasplantes renales. Este procedimiento se practica en las edades de mayor productividad y afecta diversos aspectos, entre ellos, la procreación. Con respecto a los cuidados relativos al embarazo, se diversifican las opiniones en cuanto al tiempo de espera después de un trasplante renal, así como sobre las consecuencias del uso de inmunosupresores; sin embargo, como características constantes destacan el bajo peso al nacer y los nacimientos pretérmino, que derivan en alteraciones cognitivas significativas; la severidad de éstas determina el nivel de afectación. Estas implicaciones son secundarias al uso de inmunosupresores; por lo tanto, podemos hipotetizar que de ellos se podrían derivar alteraciones en la función ejecutiva, atención, memoria, lenguaje y desarrollo motor; sin embargo, surge la duda de si hay presencia de alteraciones en los infantes expuestos a inmunosupresores y que no presentan características de bajo peso y nacimiento prétermino. Aún no se cuenta con estudios que correlacionen directamente los inmunosupresores con las alteraciones cognitivas, lo que mantiene un campo amplio a la investigación.


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