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Academia Mexicana de Neurología, A.C.

2010, Número 1

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Rev Mex Neuroci 2010; 11 (1)


Hormona concentradora de melanina (MCH): neuropéptido hipotalámico que facilita la generación del sueño

Torterolo P, Castro S, Falconi V, Lagos P

Idioma: Español
Referencias bibliográficas: 40
Paginas: 46-51
Archivo PDF: 155.13 Kb.


RESUMEN

El sistema MCHérgico está compuesto por neuronas hipotalámicas que utilizan al neuropéptido denominado hormona concentradora de melanina (MCH) como neuromodulador, y que proyectan hacia diversas regiones del sistema nervioso central, entre las cuales se destacan las áreas vinculadas con la regulación de la vigilia y el sueño. Numerosos estudios han involucrado al sistema MCHérgico con el control de la homeostasis energética. Sin embargo, estudios recientes han comenzado a mostrar un rol de este sistema en la regulación de la vigilia y el sueño. Principalmente se le ha atribuido un rol preponderante en la generación del sueño REM.
En este trabajo realizamos una breve revisión de la fisiología del sistema MCHérgico, especialmente de las evidencias que relacionan a este sistema con el control del sueño.


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