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2012, Número 1

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Rev Mex Ing Biomed 2012; 33 (1)


El estado actual y las nuevas perspectivas en sensores de glucosa no invasivos

Losoya-Leal A, Camacho-León S, Dieck-Assad G, Martínez-Chapa SO

Idioma: Ingles.
Referencias bibliográficas: 47
Paginas: 41-52
Archivo PDF: 201.28 Kb.


RESUMEN

El automonitoreo de los niveles de glucosa en la sangre proporciona a los pacientes diabéticos un método rápido para medir sus niveles de glucosa en comparación con los métodos convencionales de laboratorio. Las mediciones frecuentes permiten a los pacientes prevenir y detectar episodios de híper o hipoglucemia. Actualmente, sólo se encuentran disponibles comercialmente sensores invasivos o mínimamente invasivos. Sin embargo, a lo largo de las últimas décadas ha aumentado significativamente el trabajo de los grupos de investigación hacia el desarrollo de un sensor de glucosa no invasivo, obteniendo resultados motivadores. Una gran cantidad de técnicas han sido estudiadas e implementadas, cada una con ventajas y retos particulares. Este trabajo presenta una revisión cualitativa de los diferentes métodos no invasivos de sensado de glucosa: métodos basados en espectroscopia, métodos basados en la extracción transdérmica, fluorescencia, variaciones electromagnéticas y polarimetría. Mediante este estudio se identifican las principales ventajas y retos de cada técnica, así como las principales características y variables de desempeño para un sensor no invasivo ideal. Se discuten las técnicas más prometedoras hacia el desarrollo de un sensor con precisión clínica y verdaderamente no invasivo.


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