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2011, Número 1

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Rev Mex Anest 2011; 34 (1)


Impacto de las estatinas en el periodo perioperatorio

Carrillo-Esper R, Sosa-García JO

Idioma: Español
Referencias bibliográficas: 37
Paginas: 31-36
Archivo PDF: 315.21 Kb.


RESUMEN

Los eventos cardiovasculares son la principal complicación en el periodo perioperatorio. Las estatinas son el fármaco de elección en la prevención primaria y secundaria de patologías a nivel cardiovascular por su efecto hipolipemiante; sin embargo, sus beneficios van más allá debido a sus efectos pleiotrópicos en la modulación de la tríada patológica entre inflamación, obstrucción dinámica y trombosis en el perioperatorio. Estos efectos se han demostrado en estudios clínicos realizados en cirugía vascular no cardiaca, cirugía no cardiaca mayor, cirugía cardiovascular y cirugía cardiaca, reduciendo la incidencia de complicaciones. En conclusión, la implementación de la terapia con estatinas en el periodo perioperatorio reduce de manera significativa la morbimortalidad a corto y mediano plazo.


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