2001, Número 2
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Salud Mental 2001; 24 (2)
Teorema del trastorno obsesivo-compulsivo
Yaryura-Tobías JA, Neziroglu F
Idioma: Español
Referencias bibliográficas: 43
Paginas: 11-15
Archivo PDF: 135.88 Kb.
RESUMEN
El trastorno obsesivo-compulsivo (TOC) se caracteriza por una variedad sintomática diversa que parece reflejar varias regiones cerebrales. La hipótesis de trabajo indica que a mayor número de síntomas menor localización cerebral. Es decir se considera que la heterogeneidad sintomática no puede ser reducida a una sola área cerebral. Por lo tanto se precisa encontrar las correlaciones entre los hallazgos a nivel anatómico-histoquímico, y la semiología correspondiente al diagnóstico del trastorno del espectro TOC. Se presupone que el teorema se confirma por las lesiones cerebrales de diferente localización en pacientes con TOC. Además, la progresión histoquímica de los neurotransmisores desde la parte posterior del cerebro (
locus coeruleus y rafe) hacia adelante, y los circuitos putativos cerebrales del TOC, constituyen un factor corroborativo agregado a la hipótesis del teorema.
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