2009, Número 2
<< Anterior Siguiente >>
Rev Mex Anest 2009; 32 (2)
Xenón
Carrillo-Esper R, Sánchez-García R, Jiménez-Morales EE
Idioma: Español
Referencias bibliográficas: 31
Paginas: 120-123
Archivo PDF: 66.35 Kb.
RESUMEN
El Xenón es un gas presente en muy bajas concentraciones en la atmósfera terrestre. Tiene propiedades anestésicas y analgésicas, destacando la neuroprotección y estabilidad hemodinámica. Se ha demostrado en un buen número de estudios clínicos su seguridad y eficacia en la práctica de diversos procedimientos anestésicos/quirúrgicos pero su elevado costo de producción ha limitado su empleo en la práctica cotidiana. El objetivo de este trabajo es revisar los conceptos actuales de este interesante gas anestésico.
REFERENCIAS (EN ESTE ARTÍCULO)
Cullen SC, Gross EG. The anaesthetic properties of xenon in animals and human beings, with additional observations on krypton. Science 1951;113:580-582.
Lachmann B, Armbruster S, Schairer W. Safety and efficacy of xenon in routine use as an inhalational anaesthetic. Lancet 1990;335:1413-1418.
Goto T, Suwa K, Uezono S, Ichinose F, Uchiyama M, Morita S. The blood-gas partition coeficient of xenon may be lower than generally accepted. Br J Anaesth 1998;80:255-261.
Nakata Y, Goto T, Morita S. Comparison of inhalation inductions with xenon and sevoflurane. Acta Anaesthesiol Scand 1997;41:1157-1218.
Boomsma F, Rupreht J, Man in ‘t Veld AJ, de Jong FH, Dzoljic M, Lachmann B. Haemodynamic and neurohumoral effects of xenon anaesthesia. A comparison with nitrous oxide. Anaesthesia 1990;45:273-281.
Ma D, Wilhelm S, Maze M, Franks NP. Neuroprotective and neurotoxic properties of the ‘inert’ gas, xenon. Br J Anaesth 2002;89:739-746.
Nakata Y, Goto T, Saito H. Plasma concentration of fentanyl with xenon to block somatic and hemodynamic responses to surgical incision. Anesthesiology 2000;92:1043-1051.
De Sousa SL, Dickinson R, Lieb WR, Franks NP. Contrasting synaptic actions of the inhalational general anesthetics isoflurane and xenon. Anesthesiology 2000;92:1055-1111.
Stowe DF, Rehmert GC, Kwok WM, Weigt HU, Georgieff M, Bosnjak ZJ. Xenon does not alter cardiac function or major action currents in isolated Guinea pig hearts or myocytes. Anesthesiology 2000;92:516-528.
Jevtovic-Todorovic V, Todorovic SM, Mennerick S. Nitrous oxide (laughing gas) is an NMDA antagonist, neuroprotectant and neurotoxin. Nature Med 1998;4:460-463.
Sanders RD, Ma D, Maze M. Xenon: elemental anesthesia in clinical practice. British Medical Bulletin 2005;71:115-135.
Cullen SC, Eger EI, Cullen BF, Gregory P. Observations on the anesthetic effect of the combination of xenon and halothane. Anesthesiology 1969;31:305-314.
Nakata Y, Goto T, Ishiguro Y. Minimum alveolar concentration (MAC) of xenon with sevoflurane in humans. Anesthesiology 2001;94:611-615.
Goto T, Nakata Y, Saito H, Ishiguro Y, Niimi Y, Morita S. The midlatency auditory evoked potentials predict responsiveness to verbal commands in patients emerging from anesthesia with xenon, isoflurane, and sevoflurane but not with nitrous oxide. Anesthesiology 2001;94:782-791.
Cheng DC, Karski J, Peniston C. Early tracheal extubation after coronary artery bypass graft surgery reduces costs and improves resource use. A prospective, randomized, controlled trial. Anesthesiology 1996;85:1300-1310.
Dingley J, King R, Hughes L. Exploration of xenon as a potential cardiostable sedative: a comparison with propofol alter cardiac surgery. Anaesthesia 2001;56:829-864.
Ishiguro Y. Cardiovascular effects of xenon. Int Anesthesiol Clin 2001;39:77-84.
Lipton SA, Rosenberg PA. Excitatory amino acids as a common pathway for neurologic disorders. N Engl J Med 1994;330:613-622.
Wilhelm S, Ma D, Maze M, Franks NP. Effects of xenon on in vitro and in vivo models of neuronal injury. Anesthesiology 2002;96:1485-1491.
Ma D, Yang H, Lynch J, Franks NP, Maze M, Grocott HP. Xenon attenuates cardiopulmonary bypass-induced neurologic and neurocognitive dysfunction in the rat. Anesthesiology 2003;98:690-698.
Frietsch T, Bogdanski R, Blobner M, Werner C, Kuschinsky W, Waschke KF. Effects of xenon on cerebral blood flow and cerebral glucose utilization in rats. Anesthesiology 2001;94:290-297.
Plougmann J, Astrup J, Pedersen J, Gyldensted C. Effect of stable xenon inhalation on intracranial pressure during measurement of cerebral blood flow in head injury. J Neurosurg 1994;81:822-828.
Fujinaga M, Maze M. Neurobiology of nitrous oxide-induced antinociceptive effects. Mol Neurobiol 2002;25:167-189.
Miyazaki Y, Adachi T, Utsumi J, Shichino T, Segawa H. Xenon has greater inhibitory effects on spinal dorsal horn neurons than nitrous oxide in spinal cord transected cats. Anesth Analg 1999;88:893-897.
Horn NA, Hecker KE, Bongers B, Baumert HJ, Reyle-Hahn SM. Coagulation assessment in heathy pigs undergoing single xenon anesthesia and combinations with isoflurane and sevoflurane. Acta Anaesthesiol Scand ;45:634-638.
de Rossi LW, Horn NA, Baumert JH. Xenon does not affect human platelet function in vitro. Anesth Analg 93;635-640.
Bedi A, Mcbride WT, Armstrong MA, Murray JM. Xenon has not effect on cytokine balance and adhesion molecule expression within an idolted cardiopulmonary bypass system. Br J Anaesth 89:546-560.
Burov NE, Kornienko LI, Makeev GN, Portapov VN. Clinical and experimental study of xenon anesthesia. Anesteziol Reanimatol 56-60.
Rossaint R, Reyle HM, Schulte AM. Xenon Study Group (2003) Multicenter randomized comparison of the efficacy and safety of xenon and isoflurane in patients undergoing elective surgery. Anesthesiology 2003;98:6-13.
Goto T. Is there a future for xenon anesthesia? Can J Anesth 49:335-338.