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2004, Número 4

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Rev Med Inst Mex Seguro Soc 2004; 42 (4)


Papel del cromo y del cinc en el metabolismo de la insulina

Gómez GA, Magaña GP

Idioma: Español
Referencias bibliográficas: 53
Paginas: 342-352
Archivo PDF: 143.50 Kb.


RESUMEN

Los elementos traza se definen como los nutri-mentos que el cuerpo necesita en concentraciones de una parte por millón y comprenden menos de 0.01 % del peso corporal total. Un elemento se considera esencial si su deficiencia en la dieta resulta en una función biológica anormal que se puede prevenir o revertir con la ingesta de dicho elemento. Por ello se describen las características químicas, el papel biológico y el mecanismo de acción del cromo y el cinc sobre la regulación de la secreción de la insulina y en la expresión o actividad del receptor de insulina. Su función es contribuir para una mayor efectividad en la molécula de insulina para el transporte de glucosa. El cromo y el cinc tienen acción sobre las reacciones celulares básicas para mantener la homeostasis en el metabolismo de carbohidratos, lípidos y proteínas, así como en la producción de energía. También se informa que tienen cierta influencia para el desarrollo y progresión de la diabetes mellitus y de la hipertensión arterial. Esta breve revisión muestra la evidencia y la asociación de estos dos elementos traza sobre la acción de la insulina.


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