2008, Número 3
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Rev Inst Nal Enf Resp Mex 2008; 21 (3)
La 'nueva' displasia broncopulmonar. Parte I
Lule MMS, Guzmán GAM, Sierra VMP, Torres RJD
Idioma: Español
Referencias bibliográficas: 55
Paginas: 221-234
Archivo PDF: 138.82 Kb.
RESUMEN
En 1967 Northway
et ál, publicaron la descripción "clásica" de la displasia broncopulmonar (DBP). Los cambios ocurridos en esta entidad a lo largo de las últimas cuatro décadas han determinado que el National Heart, Lung, and Blood Institute defina los criterios actuales de la "nueva" DBP. Se da relevancia al nacimiento prematuro antes de las 32 semanas, ya que se ven interrumpidos el desarrollo alveolar y vascular normales, así como al uso terapéutico temprano del oxígeno suplementario, que aunado a la inmadurez metabólica facilita la producción de especies reactivas del oxígeno, que se comportan como vectores que ocasionan daño pulmonar en la "nueva" DBP. Gracias al constante avance tecnológico y de investigación la supervivencia de los recién nacidos prematuros extremos (‹ 1,000 g) va en ascenso, lo que conlleva a un mayor número de niños con secuelas crónicas como la DBP. De ahí que el objetivo del presente trabajo sea presentar una revisión del conocimiento actualizado de los cambios fisiopatogénicos y terapéuticos de esta entidad.
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