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Centro de Investigaciones Regionales Dr. Hideyo Noguchi, Universidad Autónoma de Yucatán

2006, Número 3

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Rev Biomed 2006; 17 (3)


Tratamiento de la enfermedad hepática crónica inducida por el virus de la hepatitis C: bases moleculares y celulares

León-Buitimea A, Leija-Salas A, Garrido-Fariña G, Reyes-Esparza J, Rodríguez-Fragoso L

Idioma: Español
Referencias bibliográficas: 109
Paginas: 195-211
Archivo PDF: 247.55 Kb.


RESUMEN

En esta revisión se analiza el estado actual del tratamiento de la enfermedad hepática crónica inducida por el virus de la hepatitis C. El presente trabajo constituye una revisión de los fármacos empleados a nivel experimental y en humanos para el tratamiento de la enfermedad hepática crónica en los últimos 10 años, así como también se hace referencia a las tendencias actuales para abordar tal padecimiento. El principal obstáculo del desarrollo de terapias antifibróticas es la lenta evolución de la fibrosis, la cual toma años e inclusive décadas en el hombre. Los avances actuales en el conocimiento de la patogénesis molecular de la fibrosis hepática y el papel de la célula estelar activada están proporcionando las bases para el desarrollo de nuevas terapias.


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