Golffier RCE, Quijano OF

Idioma: Español
Referencias bibliográficas: 29
Paginas: 207-212
Archivo PDF: 138.81 Kb.

RESUMEN

Objetivo: Evaluar la efectividad, viabilidad y función del autotrasplante esplénico en zona vascularizada (ingle) de rata, corroborando su viabilidad por medio de gammagrama hepatoesplénico.
Diseño: Experimental en animales, prospectivo, longitudinal.
Sitio: Unidad de cirugía experimental, Centro Médico ABC.
Análisis estadístico: Porcentajes como medida de resumen para variables cualitativas.
Material y métodos: Ratas Wistar hembras de 4 meses de edad y 250-300 g de peso. (Total: 22 ratas; 36 implantes). Se formaron grupos control y experimental, realizándose laparotomías, esplenectomías e implantes bilaterales inguinales. Al término de 14 semanas se realizó gammagrama hepatoesplénico.
Resultados: En los 22 animales operados se completó el protocolo en todos, sin mostrar, después del periodo de observación, ningún dato de infección o cambio en el comportamiento. Los 36 implantes mostraron una adecuada captación del radiofármaco en el gammagrama hepatoesplénico, lográndose identificar el 100% de implantes.
Conclusiones: Se demostró la viabilidad y función del autotrasplante esplénico en rata como una opción para la conservación del tejido linfoide en el organismo.

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