2023, Número 3
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Med Int Mex 2023; 39 (3)
Evaluación de la función renal y tiroidea en pacientes diabéticos e hipertensos en Tepic, Nayarit, México
Delgado-Mejía M, Delgado-Astorga C, Paredes-Casillas P, González-González E, Calvo-Vargas C
Idioma: Español
Referencias bibliográficas: 46
Paginas: 440-447
Archivo PDF: 204.77 Kb.
RESUMEN
Objetivo: Evaluar la función renal en pacientes con diabetes mellitus tipo 2 e hipertensión
arterial sistémica comparando las cifras de depuración de creatinina obtenidas
por la fórmula de Cockroft-Gault y con la depuración de creatinina en orina de 24 horas.
Materiales y Métodos: Estudio observacional y descriptivo realizado de enero de
2018 a enero de 2020, en el que se evaluaron pacientes con diagnóstico de diabetes
mellitus tipo 2 e hipertensión arterial sistémica, de uno y otro sexo, mayores de 30
años. Se evaluó la función renal con la fórmula de Cockroft-Gault contra la medición
de depuración de creatinina en orina de 24 horas en laboratorio. A todos los pacientes
se les practicaron pruebas adicionales de la función tiroidea.
Resultados: Se evaluaron 111 pacientes con diabetes tipo 2 (41 hombres y 70
mujeres), de los que 99 (89%), además, tenían diagnóstico de hipertensión arterial.
Se encontró una correlación de las pruebas de 0.659, valor de t 2.67 y valor de p de
-0.001, lo que indica que la fórmula de Cockroft-Gault y la de depuración de creatinina
en 24 horas pueden dar precisión en los resultados. De los 111 pacientes, 35 tenían
pruebas anormales de la función tiroidea.
Conclusiones: La fórmula Cockcroft-Gault es útil para dar seguimiento a la función
renal de los pacientes, ante la falta de la determinación de depuración de creatinina
en orina de 24 horas en laboratorio.
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