Oviedo SA, Zarzur JA

Idioma: Español
Referencias bibliográficas: 24
Paginas: 171-177
Archivo PDF: 69.36 Kb.

RESUMEN

Objective: In this work, a sensitive and specific Latex Agglutination Test (LAT) for detection and screening of antibodies to Hepatitis B Virus (HBV) in human serum or plasma is described. Methods and results: This test revealed a good correlation with Enzymeimmunoassay (EIA), (r:0.91) and the interassay coefficient of variation was 8-15% showing an adequate reproducibility. The sensitivity was adjusted at levels of antibody around 0.1 UI/mL and the specificity was determined by a competitive assay. Conclusion: This procedure is inexpensive and very simple, and can be applied for the studies and large scale screening of blood donors in the immune Hepatitis B plasma procurement for the production of the respective hyperimmunoglobulin.

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