Blas MJ

Language: Spanish
References: 40
Page: 58-62
PDF size: 128.85 Kb.

ABSTRACT

The use of corticosteroids in patients with sepsis and septic shock has been controversial for decades. Over the last years, a consensus has developed that pharmacologic doses of steroids in sepsis and shock septic should not be used because they do not improve survival. However recent data show far more positive results, with a reduction in mortality principally in severe septic shock patients. Several reasons may explain the recently reported positive effects of corticosteroids during sepsis. These include the treatment of a “relative” adrenal insufficiency, and the increase in adrenergic receptivity in addition to the wellknown anti-inflammatory effect. However, waiting for a confirmatory study remains mandatory before making ang solid clinical recommendation.

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