Guillén PJR, Cabrera LJO, Ricardo SYM, Martí GGM

Language: Spanish
References: 19
Page: 1333-1348
PDF size: 430.76 Kb.

ABSTRACT

Introduction: colorectal polyps are circumscribed elevations of the mucosa, most of which are asymptomatic, which constitute a risk factor for colorectal cancer.
Objective: to identify the relationship between variables such as age, sex, body mass index, endoscopic and histological and the risk of presenting dysplasia in the resected lesion.
Methods: a cohort study was carried out in patients who underwent colonoscopy and had a histological diagnosis of colon adenoma, treated at the gastroenterology service of the Carlos Manuel de Céspedes Provincial Universitario Hospital, from September 1, 2016 to December 31, August 2019.
Results: 83 patients were studied, the average age was 60.9 years, the male sex contributed 61.4% of the cases, on average the body mass index was 25 Kg/m2, the average size of the lesions It was 11.2mm, the tubular adenoma was the most frequent (88/119), the lesions were located more frequently in the sigmoid (34/119) and the sessile polypoid morphology contributed 52.9%. In the multivariate analysis, the size greater than 8mm, the distal location, the flat morphology and the hairy component increased the probability of dysplasia.
Conclusions: the appearance of dysplasia was more frequent between the fifth and sixth decades of life, as well as in lesions larger than eight millimeters. The top value of the hairy component of the adenoma, the size greater than eight millimeters, the distal location and the flat morphology are verified as the factors of greatest association with the risk of developing dysplasia in colonic adenomas.

REFERENCES

1. Eker B, Ozaslan E, Karaca H, Berk V, Bozkurt O, Inanc M, et al. Factors Affecting Prognosis in Metastatic Colorectal Cancer Patients. Asian Pac J Cancer Prev 2015; 16(7): 3015-21.

2. Dirección de Registros Médicos y Estadísticas de Salud. Anuario Estadístico de Salud, 2019. [Internet]. La Habana: MINSAP; 2020. [citado 1/2/2020]. Disponible en: https://files.sld.cu/bvscuba/files/2020/05/Anuario-Electr%C3%B3nico-Espa%C3%B1ol-2019-ed-2020.pdf

3. Aune D, Chan DS, Lau R. Dietary fibre, whole grains, and risk of colorectal cancer: systematic review and dose-response meta-analysis of prospective studies. BMJ. [Internet]. 2011 [citado 28/2/2019]. 343. Disponible en: https://www.bmj.com/content/bmj/343/bmj.d6617.full.pdf

4. Chung DC, Garber JJ. Polyps of the colon and rectum. En: Yamada’s Atlas of Gastroenterology. New Jersey: John Wiley and Sons; 2016. P. 234-237.

5. Min M, Pei D, Wenhua Z, Xiaomin S, Yan L, Bing N. Comparison of linked color imaging and white-light colonoscopy for detection of colorectal polyps: a multicenter, randomized, crossover trial. Gastroint Endosc 2017; 86(4): 724-730.

6. Andreu M, Ferrández A. Pólipos colorrectales y poliposis intestinal. En: Ponce J, ed. Tratamiento de las enfermedades gastroenterológicas. Barcelona: Doyma; 2011. P. 345-358.

7. Mascort Roca J, Marzo Castillejo M. Seguimiento de los pólipos intestinales. AMF 2016; 12(8): 467-471.

8. Day D, Jass J, Price AB, Shepherd NA, Sloan JM, Talbot IC, et al. Morson and Dawson’s Gastrointestinal Pathology 4th ed. [CD ROM]. Malden (Massachusetts): Blackwell Science; 2003.

9. Pioche M. Adenomas colorrectales. EMC Trat Med 2020; 24(1): 1-8.

10. De Lázaro y de Molina S, Marco-Doménech SF, Casanovas-Feliu E, Gaona-Morales J. Utilidad de la colonografía por tomografía o colonoscopia virtual. Anal Radiol México 2016; 15(3): 177-193.

11. Rodríguez Hernández N, Romero Pérez T, López Prieto ML, Cobas Santos CA, Martínez Carmona Y. Nivel de conocimiento sobre exámenes diagnósticos para la detección precoz del cáncer colorrectal. Rev Cienc Méd 2019; 23(2): 286-294.

12. Liu T, Jin D, Khan S, Chen X, Shi T, Dong W, et al. Clinico pathological features of advanced colorectal serrated lesions: a single-center study in china. J Dig Dis 2018; 19(4): 235-41.

13. Ben Q, An W, Jiang Y, Zhan X, Du Y, Cai QC, et al. Body mass index increases risk for colorectal adenomas based on meta-analysis. Gastroenterology 2012; 142: 762–72.

14. Moreno N, Saavedra V, Peters T, Von-Jentschyk N, Bocic G, Sanguinetti A. Prevalence of asymptomatic colonic diverticula in Chilean population as an imaging finding in abdominal and pelvic tomography. Rev Cir 2019; 71(3): 230-237.

15. Hong W, Dong L, Zippi M, Stock S, Geng W, Su CH, et al. Colonic diverticulosis is not a risk factor for colonic adenoma. Ther Clin Risk Manag 2018; 14: 531–37.

16. Arbib OS, Zemser V, Weisman YL, Gingold-Belfer R, Vilkin A, Eizenstein S, et al. Risk of advanced lesions at the first follow-up colonoscopy after polypectomy of diminutive versus small adenomatous polyps of low-grade dysplasia. Gastroint Endosc 2017; 86(4): 713-21.

17. Rôch T, Altenhofen L, Kretschmann, J, Hagen B, Brenner H, Pox Ch. Risk of Malignancy in Adenomas Detected During Screening Colonoscopy. Clinical Gastroenterol Hepatol 2018; 16(11): 1754-61.

18. Adán-Merino L, Aldeguer-Martínez M, Barrio-Antoranz J, Burdaspal-Moratilla A, Martín Chávarri S. Factors related to colorectal cancer in advanced adenomas and serrated polyps: a further step toward individualized surveillance. Eur J Gastroenterol Hepatol 2018; 30(11): 1337-43.

19. Barosa R, Mohammed N, Rembacken B. Risk stratification of colorectal polyps for predicting residual or recurring adenoma using the Size/Morphology/Site/Access score. Unit Eur Gastroenterol J 2018; 6(4): 630–638.