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ISSN 1028-4818 (Electronic)

2020, Number 2

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Mul Med 2020; 24 (2)

Demography and immunology of phenotypic variants of allergy in atopic patients aged 1-5 years. Granma. 2012-2018

Addine RBC, Marrón GR, García FM, Castellanos GI, Rivero DA

Language: Spanish
References: 20
Page: 259-277
PDF size: 525.93 Kb.


ABSTRACT

An analytical study was carried out in the Allergy Service of the Ambulatory Medical Center of Granma, in the period 2012-2018, with the aim of demographically and immunologically characterizing the phenotypic variants of allergy in 224 patients from 1 to 5 years of age. Age, sex, IgA, IgG and IgE value, complement components C3 and C4, total leukogram value, and eosinophils in blood and nasal mucosa were studied, as well as the clinical diagnosis of each phenotypic variant of allergy. Statistical processing included descriptive statistics. In addition, inferential statistics was used in the performance of bivariate analyzes through CHI 2 to identify an association with p <0.05. There were no differences in terms of sex and children of 4 and 5 years of age predominated. The order of frequency of the different phenotypes of allergic diseases was, from highest to lowest, allergic rhinitis, bronchial asthma, allergic conjunctivitis and atopic dermatitis. In the patients studied, elevated IgE and eosinophil values predominated in nasal and blood cytology and normal IgA, IgG, C3, C4 and total leukocyte count.


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